Download
slide1 n.
Skip this Video
Loading SlideShow in 5 Seconds..
Pattern of p63 mutations and their phenotypes—update PowerPoint Presentation
Download Presentation
Pattern of p63 mutations and their phenotypes—update

Pattern of p63 mutations and their phenotypes—update

108 Vues Download Presentation
Télécharger la présentation

Pattern of p63 mutations and their phenotypes—update

- - - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

  1. Pattern of p63 mutations and their phenotypes—update American Journal of Medical Genetics Part AVolume 140A, Issue 13, pages 1396-1406, 11 MAY 2006 DOI: 10.1002/ajmg.a.31271http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.31271/full#fig1

  2. Tutti gli epiteli stratificati (Epidermide, Cornea, Prostata, Mammella, Vescica, etch) sono colpiti nei topi p63 KO.

  3. terminal differentiation response to DNA damage p63 p53 CEBPs growth/differentiation cell cycle RB1 E2Fs NOTCH1 SMAD PPARs LEF1 SALL4 permeability barrier wound healing TGFb and WNT signaling stemness

  4. DNp63 TAp63

  5. ? ? ?

  6. DNp63 TAp63 TAp63