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LY294002 is a potent and specific inhibitor of phosphatidylinositol 3-kinase (PI3K), with an IC50 of 1.4 µM. This lyophilized powder, having a molecular formula of C19H17NO3 and a purity of >99% as confirmed by HPLC, is intended solely for laboratory research applications and not for diagnostic use. It is soluble in DMSO or ethanol, and should be stored tightly sealed in the dark at -20°C for up to 2 years from the shipment date. For more details, visit our website at SignaGen Laboratories.
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LY 294002 Quantity: 5 mg M.W.=307.35 Lot No.: 12578986 15875 Gaither Drive Gaithersburg, MD 20877 FAX. 301-560-4919 TEL. 301-330-5966 Email: info@signagenlabs.com Web: www.signagenlabs.com Cat # PKI-LY294-005 This product is for laboratory research ONLY and not for diagnostic use Description: Chemical Name: 2-(4-Morpholino)-8-phenyl-4H-1-benzopyran-4-one Chemical Family: Benzopyranone Molecular Formula: C19H17NO3 Purity: >99% as determined by HPLC Physical Form: Lyophilized powder Solubility: Soluble in DMSO or ethanol Research Applications: Specific and potent inhibitor of phosphatidyl-inositol 3-kinase (PI3K). IC50 =1.4 µM. Structure: References: 1. Vlahos et al (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY 294002). J.Biol.Chem. 269 5241. 2. Chasserot-Golaz et al (1998) Possible involvement of phosphatidyl-3-kinase in regulated exocytosis: studies in chromaffin cells with inhibitor LY 294002. J.Neurochem. 70 2347. Storage:Stable as lyophilized powder for 2 years at -20°C from date of shipment. Store tightly sealed in the dark. Product shipped at ambient temperature. 2006 SignaGen Laboratories