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2nd level analysis design matrix, contrasts and inference Alexander Leff

Overview Why do 2nd-level analyses? Image based view of spm stats. Practical examples of 2nd level design matrices. Correction for multiple comparisons.. 2nd Level inference. Study Group. Sample Group. . . . Inference. Sampling. In order for inferences to be valid about the study gr

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2nd level analysis design matrix, contrasts and inference Alexander Leff

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    3. 2nd Level inference

    4. Theoretical basis for 2nd level analyses Depends on whether you want to generalize your findings beyond the subjects you have studied (sample group). Usually this is the case, however: Karl’s ‘talking dog’. In a human, this happens: In humans, this happens. In this group of patients… : In patients…

    25. 2nd level analysis – what’s different? Maths is identical. Con.img at the first level are output files, at the second level they are both input and output files. 1st level: variance is within subject, 2nd level: variance is between subject. Different types of design matrix (3 examples).

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