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Silk Fibroin Wound Dressings

Silk Fibroin Wound Dressings. Used for Regenerative Healing Therapies. Sierra Obi April 1, 2013. Cutaneous Wounds. Include severe burns, animal bites, skin tears There are numerous wound dressing biomaterials on the market today

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Silk Fibroin Wound Dressings

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  1. Silk Fibroin Wound Dressings Used for Regenerative Healing Therapies Sierra Obi April 1, 2013

  2. Cutaneous Wounds • Include severe burns, animal bites, skin tears • There are numerous wound dressing biomaterials on the market today • Tested against an air permeable and a commercial wound dressing product

  3. Silk Fibroin • Promising biomaterial • Versatile for various biomedical healing applications • Mechanical robustness • Controllable degradability • Safe in acute dermal toxicity

  4. How They Work • Silk Fibroin derivative is tested on a full thickness skin wound model or an in vitro human skin model • controlled release of signaling molecules • Addition of in vivo epidermal growth factor and silver sulfadiazine

  5. Wound Healing Model

  6. Relationship of Wound Size

  7. References • http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200444/full • http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200192/full • http://www.sciencedirect.com/science/article/pii/S1742706108004054 • http://www.nejm.org/doi/full/10.1056/NEJMra0707253

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