1 / 52

Genetics

This comprehensive overview of genetics explores its foundational history, tracing the contributions of key figures such as Darwin, Mendel, and Morgan. It delves into the principles of Mendelian genetics, including monohybrid and dihybrid crosses, and examines variations beyond Mendel's initial theories, such as dominance patterns and gene interactions. The document also addresses classical genetics techniques, sex linkage, and modern detection methods for genetic issues. Keywords encapsulate the breadth of genetic research from classical studies to contemporary advancements.

lemuel
Télécharger la présentation

Genetics

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Genetics I.Introduction A.History

  2. 1. C.Darwin& A.Wallaceblending 2. G.Mendel& F.Ungermixing 3. W. SuttonChromosomal theory of Inheritance 4. T. Morgan Genes & Chromosomes plus linkage groups

  3. 5. A.Sturtevantgenetic mapping 6. F.Griffithhereditary molecule 7. O. Avery etal. DNA hereditary molecule 8. B. McKlintock Transposons

  4. 9. W.Fierssequenced viral gene 10. A.JeffreysDNA finger printing 11. 1995Viral DNA sequenced 12. 1996 yeast DNA sequenced 13. 1998 round worm DNA sequenced 14. 2003 human DNA sequenced

  5. II.Mendelian A.Experimental Design 1.Monohybrid Cross

  6. a. Definition b. Terms i.Self vs.Cross Fertilization ii.Traits vs.Characteristics

  7. c. Process

  8. c. Process Figure 14.2

  9. c. Process Figure 14.3

  10. Figure 14.4 d. Principle traits are paired and sorted

  11. d. Principle traits are paired and sorted Figure 14.5

  12. i.Gene versus Allele e. Terms iii.Dominant versus Recessive iv.Genotype versus Phenotype ii. Homozygous versus Heterozygous

  13. Figure 14.6

  14. f. Testcross Figure 14.7

  15. f. Testcross

  16. 2.Dihybrid Cross

  17. a. Definition b. Process Start by figuring out how many andtype of gametes Figure 14.8

  18. Practice Dihybrid Heterozygous cross = AaBb X AaBb Gametes AaBb = AB, Ab, aB, & ab for both Phenotypic ratio= 9:3:3:1, Genotypic ratio= 1:1:2:2:4:2:2:1:1 Dihybrid Heterozygous cross Homozygous Dominant = AaBb X AABB Gametes AaBb = AB, Ab, aB, & ab; AABB= AB only Phenotypic ratio = all dominant, Genotypic ratio = 1:1:1:1 c. Principle Each pair of alleles and chromosomessort independently into gametes.

  19. III.Variation on Mendel A.Dominance

  20. 1. Complete 2. Co-dominance AA aa Aa

  21. 3. Incomplete dominance Figure 14.10

  22. B.Gene Interactions

  23. 1. Multiple Alleles

  24. 2. Pleitrophy 3. Penetrance

  25. C.Beyond Mendel

  26. 1. Epistasis

  27. 2. Polygenic Figure 14.11

  28. 2. Polygenic Figure 14.12

  29. IV.Classical Genetics A.History

  30. 1. R.Punnet& W.Bateson??? Figure 14.9

  31. 2. T. Morgan Genes & Chromosomes, Karyotyping, plus linkage groups a. Drosophila melangastor WHY? Figure 15.3

  32. Figure 15.4

  33. b. Genetic Recombination

  34. b. Genetic Recombination Figure 15.5

  35. b. Genetic Recombination

  36. 3. A. Sturtevant Genetic Mapping Based on frequency of expression of traits showing together Figure 15.6

  37. 3. A. Sturtevant Genetic Mapping Based on frequency of expression of traits showing together Figure 15.7

  38. 3. A. Sturtevant Genetic Mapping Based on frequency of expression of traits showing together Figure 15.8

  39. B.Sex Linkage

  40. 1. Basis of SEX

  41. 1. Basis of SEX Figure 15.9

  42. 1. SEX linked inheritance Figure 15.9

  43. 2. Barr Bodies Figure 15.11

  44. V.Detection of Problems A.Techniques

  45. 1. Karyotyping 2. Amniocentesis == Cellular and Chemical Analysis Figure 14.17

  46. 3. Ultrasound 4. Chorionic Villi Sampling == Cellular and Chemical Analysis Figure 14.17

  47. 5. Fetal Tissue Sampling

  48. 6. Pedigree Analysis Figure 14.14

  49. 6. Pedigree Analysis

More Related