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Understanding and Utilizing Minimal Promoter Sequences for Enhanced Gene Expression

Explore the significance of minimal promoter sequences for gene regulation and discover key transcription factors for optimal expression. Uncover insights into regulatory elements essential for gene function.

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Understanding and Utilizing Minimal Promoter Sequences for Enhanced Gene Expression

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  1. A P1 minimal promoter sequence -361 gctagcgccggcccgaggcttccccgcctgcgctccgggtcggagccactcaggcgcgtg-301 cgcgcgtggtctcgggccgacccgagtggccgggttctctgagctccaggcccccgccgc-241 cccctcccggctcccagccaacccgtccttccctttcctcacggaatgggtccggcgctg-181 ctcggggtcgcgcgccctggacccggctcgcgctcggtctcgcgctgtcagccgctgcct-121 ggctcgcgccgccttgcgctttccctcagtcagtggcgccgaaggctccgttaagcggcg-61 gccgcggttcctgtttccgtttcttcctctcccttcagtcgggagtagcatcctccaccc-1 cagcacccctcccactctcccggcgcggccagctgcagctgaaggcagcggctgtggcga60 cgggggacggcgccgatcg -183 ctt-181 gagggcagcttttctactcagccacccgtttgagtcctcaggttttgggatctggatccc-121 caggctacagggaagagttctgcacgggaagctcatcttccagcactctgattggccagt-61 tctcactccactcactggttttcccgctctgattggccccggtggcacccggccggcgac 1 tactttgtgtgccctggcggcgcggctgg - MZF1 - PAX5 - KLF15 - NFAT/IRF7/PU1 + MEIS1 - VMAF - IRF3/PRDM1 - VMYB + AREB6 + AREB6 - SPIB / IRF3 / NFAT / ELK1 - OLF1 - EVI1 - KLF15 + AP4 - KLF15 - PAX5 B P2 minimal promoter sequence - NKXH - MYB - Activator - CDP Protein 2 - HELT -YBXF + ETS1 + Gfi-1 + MEL1 - CDP + NKX3 + Gfi-1 + IKRS

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