250 likes | 340 Vues
Highlights from the 14 th Annual Report. Catriona Shaw Research Fellow UK Renal Registry. UKRR Audit Day , October 2012. demography. UK incident RRT rates between 1980 and 2010. Median age of incident patients in each centre in 2010. Prevalence rate of RRT patients per million population
E N D
Highlights from the 14th Annual Report Catriona Shaw Research Fellow UK Renal Registry UKRR Audit Day, October 2012
demography UK incident RRT rates between 1980 and 2010
Prevalence rate of RRT patients per million population by age and gender on 31/12/2010
Population aged 65 and over, 2011 England and Wales local and unitary authorities
Ethnicity and standardised prevalence ratios for all PCT/HB areas by percentage non-White on 31/12/2010 (excluding areas with <5% ethnic minorities)
Age profile of prevalent RRT patients by modality on 31/12/2010
Co morbidity Growth in prevalent patients by treatment modality at the end of each year 1997–2010 • Changes 2005-2010 • (pmp) • -5.9% PD, • +4.1% HD, • +4.6% Tx Growth of home haemodialysis +23% (2010 data)
Mean comorbidity score by age group Fotheringham, J et al. UKRR Annual Report 2012
survival Trend in 1 year after 90 day survival by first established modality 2003–2009 (adjusted to age 60) (excluding patients whose first modality was transplantation)
Kaplan–Meier survival of incident patients 1997–2009 cohort (from day 90), without censoring at transplantation
Survival one-year after 90 days, adjusted to age 60, 2009 incident cohort
Median age of incident CKD5 and incident RRT patients by renal centre Ford, D et al UKRR Annual Report 2010, Nephron Clinical Practice +Unpublished work
International comparison of RRT incidence rates in 2009 Data from USRDS
Haematological and biochemical parameters Funnel plot of percentage of HD patients with Hb ≥10 and ≤12 g/dl by centre in 2010
Percentage of haemodialysis patients with phosphate within the range specified by the RA clinical audit measure (1.1–1.7mmol/L) by centre in 2010
Funnel plot of percentage of haemodialysis patients with PTH within range (16–32 pmol/L) by centre in 2010
Transplant population • Increase in renal transplantation from all sources of organs • Inclusion of eGFR slopes in the analysis for the first time • 9734 individuals included in eGFR slope analysis • Steeper slopes were seen in females, ethnic minorities, diabetes, younger individuals
Cause of death by modality for prevalent patients on 1/1/2010
Infective complications Box and whisker plot of MRSA rates by renal centre per 100 prevalent HD/PD patients by reporting year
Number of MSSA bacteraemia episodes by access and renal centre: 1/01/2011 to 30/06/2011
1995: Treatment of adult patients with renal failureRecommended standards and audit measures
opportunities • CKD stage 5 patients to understand conservative and withdrawal issues to allow adjustment for survival and other outcomes (quality of life) • AKI • Challenge our current boundaries in therapies • Specific need for research focused on improving outcomes in the elderly multi-morbid population • New collaborations with external organisations (CPRD, allied renal industries)- help improve drug data, examine outcomes, pragmatic RCT’s?, causal inference methodologies
WE ARE ALL GETTING BETTER AT STOPPING DEATH IN CKD Our GP, cardiac and diabetology colleagues will safely carry CKD patients into the hands of nephrologists