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Rethinking Diagnoses: A Statistical Approach to Health

Questioning existing medical diagnoses like ADHD, proposing a statistical intervention based on normal distribution, examining score distributions for ADHD questionnaire, addressing methodological challenges, and advocating for open science practices to prevent p-hacking.

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Rethinking Diagnoses: A Statistical Approach to Health

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  1. ADHD doesn’texist? Astatisticalapproach

  2. Normal? • Nurse: she is waytoolight • Me: ???? • Nurse: shebelongs to the lowestpercentile! • Me: Wow, Should I give more food? • Nurse (glad that I amsoclever):Yesyes, youcertainlyshould • Me: soshewillbeheaviernext time? • Nurse: Suresure • Me: butthen, another baby willbe in the lowestpercentile!

  3. Who is sick? According to proposed criteria, a vast majority of elderly will be classified chronic patient. More pills will be sold.

  4. BloodPressure distributionwho is sick? Pre-hypertension! Morbidity correlates with pressure NORMAL INTERVENTION ABNORMAL

  5. Proposal • 1: No interventions on the basis of X standard deviations but on the basis of deviations from a normal distribution or validated process model of disease. Allow normal variation! • 2: Testing the score-distributions of ADHD Questionnaire (general population). • Using the score distribution for autism disorders as a control?

  6. Methodological issues • In a homeostatic system the null distribution differs from normal? • Null distribution might be skewed due to asymmetric floor and ceiling constraints. • What is the effect of bin width on the sensitivity of testing a distribution vs. a null distribution. • Multiple causes might obscure each other.

  7. On-linepreregistration • Questionable research practices • Majority of researchers do p-hacking • Can be prevented by proper pre-registration • Open Science Framework • Fits the scientific work flow • Each edit is timestamped. • Psychological Science will stimulate • http://openscienceframework.org

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