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  1. Supplementary Figure 1. A: Raw crossing threshold data for gene expression analyses in 24 wk old striatum of wild-type (WT) and R6/1 transgenic (TG) mice housed in standard non-enriched (SH) or environmentally enriched (EE) conditions. Genes are: Atp5b (ATP synthase subunit 5b), Eif4a2 (eukaryotic initiation factor 4a2), Yhwaz (phospholipase A2), TG (exon 1 transgene-specific), Drd2 (dopamine D2 receptor), Darpp32 (dopamine and cAMP regulated neuronal phosphoprotein), Igfbp5 (insulin-like growth factor binding protein 5 precursor), Penk1 (preproenkephalin), Mbp (myelin basic protein), Uchl1 (ubiquitin carboxyl-terminal hydrolase L1), A2a (Adora2a, adenosine A2a receptor), Hpca (hippocalcin), Itpr3 (inositol 1,4,5-triphosphate receptor 3), Knck1 (potassium channel, subfamily K, member 2), Nr4a2 (nuclear receptor subfamily 4, group A, member 2), Usp2 (Ubiquitin specific peptidase 2), Hdh (Huntingon’s disease homologue). B: Raw crossing threshold data for gene expression analyses in 24 wk old cortex of WT and R6/1 transgenic mice housed as in A. Canx (calnexin), Bdnf (brain derived neurotrophic factor). C: Bdnf exon-specific expression ratios with respect to the geometric mean of 2 reference genes, Atp5b and Canx. Bars = SEM.

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