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bcj201315x3

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bcj201315x3

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  1. ** ** ** ** Figure S3. ATL-induced apoptosis in the MCL Z-138 cell line is mediated by caspase activation. Z-138 cells were preincubated without (Control) or with 50 mM z-VAD-fmk for 1 h, and then in the absence (Control) or presence of 10 mM perifosine (PRIF) or edelfosine (EDLF) for 24 h. Apoptosis was quantitated as the percentage of cells in the sub-G0/G1 region following cell cycle analyses by flow cytometry. Data shown are means + SD of three independent experiments. Asterisks indicate values that are significantly different from untreated control cells at p < 0.01 (**) level by Student’s t-test.

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