1 / 12

Is Gingko Biloba an Effective Alzheimer’s Treatment?

Is Gingko Biloba an Effective Alzheimer’s Treatment?. William Hopper. History. Oldest known fossil 5,000 yrs. old-China Avg. Life span 1,000 yrs. Withstood atomic bomb during WWII First introduced in US 1784 Largest plantations worldwide-Sumter, SC and Virginia. What is Gingko?.

linus-levy
Télécharger la présentation

Is Gingko Biloba an Effective Alzheimer’s Treatment?

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Is Gingko Biloba an Effective Alzheimer’s Treatment? William Hopper

  2. History • Oldest known fossil 5,000 yrs. old-China • Avg. Life span 1,000 yrs. • Withstood atomic bomb during WWII • First introduced in US 1784 • Largest plantations worldwide-Sumter, SC and Virginia

  3. What is Gingko? • Maidenhair tree • Leaves • Fan shaped • Green in summer • Gold in fall • Fruit • Plumlike • Smooth • Silvery white seed

  4. Structure and Growth • Grows 20-30 m tall, 9 m wide • Dioecious • Prefers partial sun, moist, deep, sandy soil • Resistant to disease, insects, and fungus

  5. Medicinal Uses • Seeds • Asthma • Leucorrhea • Leaves • Cardiovascular • Inhibits Platelet Activating Factor • Alzheimer’s • EGB 761

  6. Alzheimer’s Basics • Most Common form of Dementia • Associated w/ amyloid beta peptide aggregation • Gradual cognitive decline • Loss of synapses between nerves

  7. Research • 1st Clinical US study in 1997-New York Institute for Medical Research • Results: Participants showed improved cognitive function and social behavior, but not on a doctor’s assessment • Study in 2000, however, showed there to be no difference between patients treated with EGB 761 vs cholinesterase inhibitors

  8. Further Research • Study of effect on rats showed an increase in cognitive function and increased life span on avg. 4 months. • Treatment w/ Gingkolides A and B show resistance to amyloid beta aggregation so could be useful if they can cross blood brain barrier

  9. Chemicals in Gingko • 24% flavone glycosides • Antioxidant activity • Increases circulation • 6% terpene lactones • Increases circulation • Protects nerve cells

  10. Side Effects • Excessive bleeding • Contains alkylphenols • Increased insulin secretion, but no effect on glucose levels possible Type 2 diabetes link

  11. Conclusion • Possibly good for mild to moderate cases • Need more research-better understanding of Alzheimer’s • Too many over the counter claims • “Improves Memory and Concentration” but not enough for FDA approval yet

  12. References • Westall, Kelly Ethnobotanical Leaflets www.siu.edu/~ebl/leaflets/gingko2.htm • “Gingko” emedtv http://alzheimers.emedtv.com/gingko-biloba/gingko.htm • “Gingko Proves to be an Effective AD Treatment” AlzheimerSupport.com www.alzheimersupport.com/articles/alz31.cfm • Botany.com www.botany.com/gingko.html • “Gingko Biloba” www.naturalmedicine.com/healthnotes.php?productid=16& ContentId=2096000 • “Gingko Improves Brain Function, Extends Life Span” AlzheimerSupport.comwww.alzheimersupport.com/library/showarticle.cfm?ID=1492 • Bate, Clive, Mourad Tayebi and Alvin Williams. “Gingkolides Protect Against amyloid beta Mediated Synapse Damage in vitro” Molecular Neurodegeneration 7 January 2008

More Related