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Version 10

Version 10. Mission; Foster adoption of…. pragmatic and cost effective standards for accurate and reproducible longitudinal quantitation of biologic parameters with clinical relevance and known sigma. H/o Commercial Dx Individuals - thresholds Categorical, staging Workflow/# studies

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Version 10

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  1. Version 10

  2. Mission; Foster adoption of… • pragmatic and cost effective standards for • accurate and reproducible • longitudinal • quantitation of • biologic parameters • with clinical relevance • and known sigma

  3. H/o Commercial Dx Individuals - thresholds Categorical, staging Workflow/# studies Binary – choice of Rx Biomarkers become Dx Populations – means Continuous, quantitative Automation/bias Longitudinal – Rx effect Monitoring Rx Benefit = Individualized MedicineConvergence of Biomarkers and Diagnostics Quantifying the effects of drugs in development may beg access to biomarkers as diagnostics

  4. RSNA ’10 and on Milestone horizon/PET-CT RSNA ‘09 Calibration Phantoms Characterization Lo, Hi rads RoI Definition* Dynamic Range lesion size** RSNA ‘08 Interoperability of Results Encoding Image Quality Metrics Quantitation Computation Documentation of terms High High High High Medium High Value H, M, L High High High High High Feasibility H, M, L High *Adoption 2010-11, but Define by 2008 Priority H, M, L N/A Quick Hits **Ideal Phantom 2010-11 Current phantom by 2008 Chair H, M, L TBN Clunie

  5. Version 10

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