Analysis of Gene Expression Patterns in Human Embryonic Stem Cells and Various Tissues
This study explores the expression patterns of key genes such as NANOG, LEFTY1, and others across different human tissues including oocytes, testis, and various organs such as the kidney and cardiovascular system. We focus on the contrasting expression in embryonic stem cells (hESCs) compared to fibroblasts, as well as the role of transcription factors like FOXM1, KLF5, and others. The data includes detailed gene expression comparisons and highlights critical insights into developmental biology and tissue-specific functions.
Analysis of Gene Expression Patterns in Human Embryonic Stem Cells and Various Tissues
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Presentation Transcript
POU5F1 OTX2 NANOG LEFTY1 LEFTY2 THY1 FZD7 LIN28 CGA hESC Fibroblasts Oocytes Testis Nervous system Digestive tract Kidney Cardio- vascular system Spleen TE Others Blood Placenta PGF ALPPL2 PPARD Figure S5 – Bai et al.
IRX3 IRX1 PBX1 HEY2 FOXM1 ABCG2 MMP9 GAGE2A hESC TE Fibroblasts Oocytes Testis Nervous system Digestive tract Kidney Cardio- vascular system Spleen Others Blood Placenta GAGE3 MAGEB2 XAGE2 PAGE1 Figure S5 – Bai et al.
DNMT3A DNMT3B GCM1 IRX4 PPARG ZFP42 MYCN hESC TE Fibroblasts Oocytes Testis Nervous system Digestive tract Kidney Cardio- vascular system Spleen Others Blood Placenta NR6A1 GATA2 CEBPA DLX4 Figure S5 – Bai et al.
ELF3 KLF5 MAFK MSX2 MXD1 PPP1R13L TFAP2C TFEB Oocytes Testis Nervous system Digestive tract Kidney Cardio- vascular system Spleen hESC TE Fibroblasts Others Blood Placenta TP63 KRT18 PITX2 Figure S5 – Bai et al.
