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PemPlant Co.

This update from PemPlant Co. outlines the current status of our projects regarding untreated glass and titanium substrates. We are investigating antibacterial properties, mechanical stability, and bactericidal testing involving Staphylococcus epidermidis. Detailed task breakdowns and a Gantt chart are provided, forecasting completion by May 1. Key experiments include nanoindentation, AFM surface imaging, and cytophillic testing to assess fibroblast interactions. This initiative aims to enhance our understanding of polymeric coatings for medical applications.

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PemPlant Co.

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  1. E P M PemPlant Co. February 15, 2007 Update Maricela Delgadillo Kay Furman Yushan Kim PemPlant Co.

  2. Status overview • PAA/PAAm on untreated glass underway • Ti substrate ordering investigated PemPlant Co.

  3. Gantt Chart • Detailed task breakdown • Open Workbench Link: • Forecasted completion by 1 May PemPlant Co.

  4. Experimental Overview • Glass PEM antibacterial properties • Ti PEM • Stability • Mechanical characterization • Bactericidal testing • Modified Ti PEM • Mechanical characterization • Bactericidal testing • Cytophillic testing PemPlant Co.

  5. Glass PEM Antibacterial Properties • Staph. Epidermidis • 1 h, 2 h, and 4 h incubations • Microscopy • Both anticipated bactericidal • Serve as “dry run” PAAm=Polyacrylamide PemPlant Co.

  6. Ti PEM Stability Testing • Test duration 2 wks-1 mo • Ti PEM stability unknown • Visual observation PemPlant Co.

  7. PEM Mechanical Characterization • Experiments: • Nanoindentation • AFM surface imaging • AFM scratch test • Handling simulation • Compare to Previous Glass PEM Nanoindentation PemPlant Co.

  8. PEM Antibacterial Properties • Staph. Epidermidis • 1 h, 2 h, and 4 h incubations • Microscopy PemPlant Co.

  9. Modified Ti Mechanical Characterization • Biological additive to be selected • Experiments: • Nanoindentation • AFM surface imaging • AFM scratch test • Handling simulation PemPlant Co.

  10. Modified Ti Antibacterial and Cytophillic Properties • Fibroblast eukaryotic cells • 1 day, 3 days • Staph. Epidermidis • 1 h, 2 h, 4 h • Microscopy PemPlant Co.

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