1 / 21

PERIOPERATIVE MANAGEMENT OF TRAUMATIC BRAIN INJURY

PERIOPERATIVE MANAGEMENT OF TRAUMATIC BRAIN INJURY. OBJECTIVE 1.REVIEW IMPORTANCE OF SECONDARY ISCHEMIC BRAIN INJURY AFTER HEAD INJURY 2.ANESTHETIC MANAGE OF ACUTE HEAD INJURY 3.EVIDENCE BASE MEDICINE FOR INTENSIVE CARE OF HEAD INJURY. INTRODUCTION.

lot
Télécharger la présentation

PERIOPERATIVE MANAGEMENT OF TRAUMATIC BRAIN INJURY

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PERIOPERATIVE MANAGEMENT OF TRAUMATIC BRAIN INJURY • OBJECTIVE • 1.REVIEW IMPORTANCE OF SECONDARY ISCHEMIC BRAIN INJURY AFTER HEAD INJURY • 2.ANESTHETIC MANAGE OF ACUTE HEAD INJURY • 3.EVIDENCE BASE MEDICINE FOR INTENSIVE CARE OF HEAD INJURY

  2. INTRODUCTION • PERIOPERATIVE IS GUIDE TO DECREASE BURDEN OF SECONDARY BRAIN INJURY BY 2 STRATEGIES • 1.MAINTAIN CARDIOPULMONARY STABILITY • 2.MONITOR PHYSIOLOGIC VARIABLE REFLECT SECONDARY BRAIN INJURY • SECONDARY BRAIN INJURY ASSOCIATE WITH • 1.POST INJURY HYPOTENSION[ esp sBP<90]

  3. INTRODUCTION • 2.HYPOXEMIA • 3.INTRACRANIAL HYPERTENSION • CONTRIBUTING MECHANISM OF SECONDARY TBI • 1.CEREBRAL VASOCONSTRICTION • 2.IMPAIR AUTOREGULATION • TO MINIMIZE M&M TO PREVENT HYPOTENSION

  4. CEREBRAL CIRCULATION RESPONSES TO ACUTE HEAD INJURY • TBI IS CHARACTERIZED BY • 1.DECREASE CBF[ ESP < 18 CC/100G/MIN] • 2.IMPAIR AUTOREGULATION • 3.INCREASE ICP • HYPERVENTILATION DECREASE CBF AND DECREASE BRAIN OXYGENATION • 1/3 OF PT AFTER TBI, CBF CHANGEED AS CPP CHANGED • THEN TO CONTROL ICP MAINTAIN CPP AND THEN CBF

  5. PREANESTHETIC STABILIZATION AND ASSESSMENT • MINIMIZE TIME TO RESUSCITATE AND ASSESSMENT • 1.ASSOCIATE INJURY • 2.RESUSCITATION DETAIL • 3.GCS [ ESP <=8 IS SEVERE TBI] TELL PROGNOSTIC FACTOR

  6. EMERGENT AIRWAY CONTROL • INTUBATION SEQUENCE • 1.PRESERVE OXYGENATION • 2.ELIMINATION CO2 • 3.PREVENT ASPIRATION • 4.MAINTAIN SYSTEMIC BP • 5.MINIMIZE INCREASE ICP • 6.AVOID AGGRAVATION OF CERVICAL SPINE INJURY[10% OF TBI] BY MANUAL IN LINE AXIAL STABILIZATION

  7. EMERGENT AIRWAY CONTROL • 7.BLIND NASAL INTUBATION CAUTION IN • 7.1 MAXILLARY FX • 7.2 BASILAR SKULL FX • DURING INTUBATION CADIOPULMONARY SHOULD STABILITY AVOID COUGHING,STRAINING,HYPERCARBIA,HYPOXEMIA • THIOPENTHAL AND ETOMIDATE DOSE DEPENDENTLY REDUCE CMRO2, CBF, ICP

  8. EMERGENT AIRWAY CONTROL • SUPPLEMENTATION WITH LIDOCAINE IV WILL BLUNT SYMPATHETIC RESPONSES AND LIMIT ICP • MIDAZOLAM DECREASES CBF AND DOES NOT INCREASE ICP • PROPOFOL REDUCES ICP AND CBF BUT INDUCED HYPOTENSION • AFTER ACUTE TBI, SUCCINYLCHOLINE IS APPROPRIATE DESPITE TIS MAKE TRANSIENT INCREASES IN ICP

  9. FLUID RESUSCITATION • PROMPT RESTORATION OF SYSTOLIC AND MAP AND THEN MAINTAIN CPP [ CPP = MAP-ICP ] • HYPOTONIC SOLUTION [ LRS ] INCREASE BRAIN WATER CONTENT THAN 0.9 %NSS • DRUMMOND ET AL. DEMONSRTATED COLLOID MAINTAINED LOWER BRAIN WATER THAN CRYSTALLOID AND THEN DECREASE ICP

  10. INTRAOPERATIVEMANAGEMENT • MONITOR : EKG, A-LINE,O2SAT,FOLAY,CAPNOGRAPHY • PULMONARY ARTERIAL CATHETERIZATION USE TO TELL ADEQUACY OF INTRAVASCULAR VOLUMN OR CARDIAC PERFORMANCE • RESTRICTION OF FLUID IS CONTROVERSIAL,NO CLINICAL EVIDENCE SUPPORT • EARLY NONNEUROLOGIC SURGERY NOT TO WORSEN OUTCOME OF MULTIPLYTRAUMATIZED PATIENTS TBI

  11. INTRAOPERATIVEMANAGEMENT • IN NONNEUROSURGERY IN TBI ,MONITOR ICP IS IMPORTANT BY • 1.JUGULAR VENOUS BULB CATHETERIZATION TELL MIX CEREBRAL VENOUS BLOOD THAT REFLECT CEREBRAL ISCHEMIA EVEN ONE EPISODE • 2.BRAIN TISSUE PO2 IS DIRECT METHOD THAT REFLECT ISCHEMIA AND CHANGED IN CPP AND PaCO2 • BOTH METHOD SENSITIVITY 50% DETECT CEREBRAL ISCHEMIA

  12. INTRAOPERATIVEMANAGEMENT • ACUTE INCREASE ICP IMMIDIATE MANAGEMENT BY • 1.HYPERVENTILATION : RAPID EFFECTIVE • 2.DIURETIC : MANNITOL ,FUROSEMIDE • 3.SURGERY • MAINTENANCE OF ANESTHESIA VARIABLY INFLUENCE CBF,CBV,CMRO2,AUTOREGULATION,RESPONSIVENESS TO PaCO2

  13. INTRAOPERATIVEMANAGEMENT • BARBITURATES ,BZP,NARCOTIC,HYPOCAPNIA APPEAR TO LIMIT N2O-INDUCED INCREASE CBF AND ICP • N2O AVOID IN PNEUMOCEPHALUS AND PNEUMOTHORAX • USE LOW CONCENTRATION [< 0.5 MAC] OF ISOFURANE OR SEVOFLURANE • AVOID SUFENTANIL AND ALFENTANIL BECAUSE INCREASE ICP

  14. INTRAOPERATIVEMANAGEMENT • IMPORTANCE ADJUVANT DRUGS • 1.NON-DEPOL NMB [ SHOULD NOT REDUCE BP OR INCREASE CBF AND ICP] : VERCURONIUM,ROCURONIUM IS RECOMMENDED • 2.BETA-BLOCKER OR LIDOCAINE DEMINISH HYPERTENSON OR TACHYCARDIA • PaO2 SHOULD MAINTAIN AT LEAST >60 mmHg BECAUSE HYPOXIA INCREASE CBF

  15. INTRAOPERATIVEMANAGEMENT • PaO2 FROM 100-150 mmHg TO 200-250 mmHg IMPROVE CEREBRAL VENOUS OXYGENATION IN PATIENT AFTER TBI • TREATMENT OF SYSTEMIC HYPERTENSION • 1.NTP,NTG,HYDRALAZINE : UNACCEPT CEREBRAL VASODILATATION IN WHO HAVE DECREASE INTRACRANIAL COMPLIANCE • 2.BARBITURATE,NARCOTIC,BZP REDUCE MAP WITH LESS RISK

  16. INTRAOPERATIVE MANAGEMENT • 3.LABETALOL [ALPHA+BETA BLOCKER] REDUCE MAP AND ICP • EMERGENT MANAGE HYPOTENSION REQIURE SHORT TERM INFUSE VASOCONSTRICTORS TO MAINTAIN CPP UNTIL HYPOVOLEMIA IS CORRECTED • WHEN DURA IS OPENED ,HYPERTENSION SHOULD BE CONTROLLED BECAUSE INCREASE CPP MAY INCREASE CBF

  17. INTRAOPERATIVEMANAGEMENT • AFTER BRAIN SURGERY,MOST PATIENT ARE NEITHER AWAKED NOR EXTUBATED UNLESS • 1.PREOPERATIVE CONSCIUOS NORMAL • 2.PREOPERATIVE CONSCIOUS RAPIDLY DECLINED • PROFOUND PARALYSIS REDUCED CHANGED ICP WHEN TRANSFER TO ICU • DURING TRANSPORT SHOULD MONITOR BP,O2sat,CAPNOMETRY [ ICP MONITORING IF AVALIABLE

  18. INTRAOPERATIVE BRAIN PROTECTION • HIGH DOSE PENTOBARBITOL IMPROVE ICP CONTROL AND REDUCTION EXTRACELLULAR LACTATE AND EXCITOTOXIC AMINO ACIDS GLUTAMATE AND ASPARTATE • MILD HYPOTHERMIA [ 34 *C] WILL REDUCE CMRO2 AND ICP AND IMPROVED OUTCOME AFTER SEVERE TBI, THUS REWARMING PATIENT SHOULD BE SLOWLY BUT NOW NO EVIDENCE BASE

  19. INTRAOPERATIVE BRAIN PROTECTION • HOWEVER, HYPERTHERMIA SHOULD BE CORRECTED BECAUSE THERE HAVE EVIDENCE THAT SMALL ELEVATIONS IN TEMPERATURE INCREASE RELEASE OF EXCITOTOXIC AMINOACIDS DURING ISCHEMIC EPISODES • GOAL TO MAINTAIN CPP ABOVE TARGET LEVEL[>70 mmHg] WITH HOPE THAT BETTER CBF WILL BE ASSURED TO IMPROVE OUTCOME AFTER TBI

  20. INTRAOPERATIVE BRAIN PROTECTION • ROBERTSON ET AL COMPARED CBF-TARGET STRATEGY OF MAINTAIN CPP>70 mmHg WITH ICP TARGET STRATEGY FOUND NO DIFFERENCE IN OUTCOME • MONITORING CEREBRAL OXYGENATION AND PROMPT TREATMENT WHEN DESATURATION OR HYPOXEMIA[ TO PREVENT SECONDARY ISCHEMIC INJURY] ARE MORE EFFECTIVE THAN CORRECT SYSTEMIC VARIABLE[ HYPOTENSION]

  21. TRANSFER OF PATIENTS TO THE INTENSIVE CARE UNIT • DURING TRANSFER VENTILATION,OXYGENATION,CPP MUST BE CAREFULLY MAINTAINED. • MINITOR BP,CAPNOGRAPHY,O2sat,ICP MONITORING • DURING EMERGENCE RESULT IN INCREASE IN BP,ICP, ADDITIONALSEDATIVE,NARCOTIC,LABETALOL MAY BE REQUIRED • ALVEOLAR VENTILATION MUST BE CAREFULLY SUPPORTED AND MONITORED UNTIL TO ICU

More Related