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Mendelian Genetics K. Sathasivan

Basic genetic terms. Mendel's laws of inheritance. Complexities of genetic expression. Mendelian genetics in Humans. Mendelian Genetics K. Sathasivan. Basic Terms. Figure 14.0 Painting of Mendel. Figure 14.0x Mendel. Figure 14.x1 Sweet pea flowers.

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Mendelian Genetics K. Sathasivan

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  1. Basic genetic terms. Mendel's laws of inheritance. Complexities of genetic expression. Mendelian genetics in Humans Mendelian GeneticsK. Sathasivan

  2. Basic Terms

  3. Figure 14.0 Painting of Mendel

  4. Figure 14.0x Mendel

  5. Figure 14.x1 Sweet pea flowers

  6. Allele pairs segregate (separate) during gamete formation and the paired condition is restored by the random fusion of gametes at fertilization. Law of Segregation

  7. Figure 14.1 A genetic cross

  8. Figure 14.2 Mendel tracked heritable characters for three generations

  9. Table 14.1 The Results of Mendel’s F1 Crosses for Seven Characters in Pea Plants

  10. Figure 14.x2 Round and wrinkled peas

  11. Figure 14.4 Mendel’s law of segregation (Layer 1)

  12. Figure 14.4 Mendel’s law of segregation (Layer 2)

  13. Figure 14.5 Genotype versus phenotype

  14. Figure 14.6 A testcross

  15. Law: The segregation of each allele pair is independent of other allele pairs. The individual allele pairs need to be located on separate loci, far from each other to allow independent assortment during gamete formation. Law of Independent Assortment

  16. Figure 14.3 Alleles, alternative versions of a gene

  17. Figure 14.7 Testing two hypotheses for segregation in a dihybrid cross

  18. Figure 14.8 Segregation of alleles and fertilization as chance events

  19. Incomplete Dominance Co-dominance Epistasis Polygenic characters Pleiotropy Environmental effect Developmental effect Complexities of Gene Expression

  20. Figure 14.9 Incomplete dominance in snapdragon color

  21. Figure 14.9x Incomplete dominance in carnations

  22. Figure 14.10 Multiple alleles for the ABO blood groups

  23. Figure 14.10x ABO blood types

  24. Figure 14.11 An example of epistasis

  25. Figure 14.12 A simplified model for polygenic inheritance of skin color

  26. Figure 14.13 The effect of environment of phenotype

  27. Figure 14.15 Pleiotropic effects of the sickle-cell allele in a homozygote

  28. Recessive Traits Albinism, Cystic Fibrosis, Tay Sachs, Sickle Cell, PKU, Galactosemia Dominant Traits Achondroplasia Alzheimer’s, Huntington, Hypercholesterolemia Mendelian Inheritance in Humans

  29. Heart Disease Cancer Diabetes Alcoholism Schizophrenia Manic Depression Polygenic Traits

  30. Figure 14.14 Pedigree analysis Dominant Traits Widow’s Peak, Freckles and Free Ear Lobe

  31. Figure 14.16 Large families provide excellent case studies of human genetics

  32. Amniocentesis Chorianic Villus Sampling (CVS) Ultrasound Fetoscopy Screening of embryos Early Detection of Human GeneticDisorders

  33. Figure 14.17 Testing a fetus for genetic disorders

  34. Basic genetic terms. Genotype, phenotype, gene, allele, dominant, recessive, homozygous and heterozygous etc. Mendel's laws of inheritance. Law of segregation and law of independent assortment. Complexities of genetic expression. Incomplete dominance, codominance, epistasis, pleiotropy etc. Mendelian genetics in Humans Dominant and recessive disorders and early detection techniques Summary

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