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Pheochromocytoma is a rare tumor that produces excess catecholamines, affecting heart rate, blood pressure, and metabolism. This guide explores essential topics, including the role of epinephrine and norepinephrine, symptoms such as hypertension and cardiac arrhythmias, as well as diagnostic tests like CT, MR, and I131-MIBG. Treatment strategies are highlighted, with an emphasis on alpha and beta blockers, cold stimulation tests, and options for management. It discusses the long-term outlook, with over 75% achieving normal health within a month, and emphasizes the importance of monitoring during and after treatment.
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pheochromocytom 7 (3) Baiyan
Where are you from? • Where are you living now? • What about the family members?
E: epinephrine NE:norepinephrine ACTH CRH GHRH CGRP ANP VIP NPY SS AM
work • αreceptor: α1, α2 • smooth muscle + or – • β receptor: β1, β2 • smooth muscle - • heart +
Hypertension hypotension shock • Cardiac arrhythmia heart failure • Metabolism arrhythmia :fat,glucose,K,Ca
CA VMA MN NMN HVA • Stimulate test: cold • glucagon • Inhibit test: regitine • clonidine
CT • MR • B • I131-MIBG
Operation αrecepter blocker βrecepter blocker Blood volume preparetion
The end • 75% one month normal • 25% drug treatment • <10% coming again • The bad ones <5% five years