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Archived File. The file below has been archived for historical reference purposes only. The content and links are no longer maintained and may be outdated. See the OER Public Archive Home Page for more details about archived files. NIH Director’s Pioneer Award Program. Jeremy M. Berg

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  1. Archived File The file below has been archived for historical reference purposes only. The content and links are no longer maintained and may be outdated. See the OER Public Archive Home Page for more details about archived files.

  2. NIH Director’s Pioneer Award Program Jeremy M. Berg National Institute of General Medical Sciences May 22, 2006

  3. Molecular Libraries and Imaging Re-engineering the Clinical Research Enterprise Building Blocks, Biological Pathways and Networks Structural Biology Public-Private Partnerships Implementation Groups Bioinformatics and Computational Biology High-risk Research Interdisciplinary Research Nanomedicine Clinical Enterprise New Pathways to Discovery Research Teams of the Future

  4. NIH Director’s Pioneer Award • Intended to support individuals as opposed to projects • Significantly simplified nomination (application) process • Five-page essay • 3 letters of reference • Single representative work

  5. NIH Director’s Pioneer Award 2004 • Multi-tiered review process • Nominations review by NIH staff, outside reviewers • Approximately 1/3 of nominees invited to apply • Applications reviewed by outside reviewers • ~20 finalists interviewed at NIH for final review • Final review by Advisory Committee to Director, NIH • Nine awards made in September 2004 • >1300 nominations • Each award $500K direct costs per year for five years • >51% commitment of effort required

  6. 2004 NIH Director’s Pioneer Awardees

  7. NIH Director’s Pioneer Award 2005 • Program re-announced for FY2005 with minor modifications • Self-nominations only • Women, underrepresented minorities, and individuals in early to mid-career especially encouraged to apply • Direct discussion of why NDPA award is appropriate requested in essay • More than 800 nominations received

  8. NIH Director’s Pioneer Award 2005 • External review of nominations (Yes or No) • External review of applications • 3 reviewers, 2 from designated field, 1 from outside • Review criteria • Innovation • Motivation • Potential impact • Scoring • Each category scored 1-5 (5 best) • Overall score (1-5) • Each reviewer listed Top 4 applicants • 20 finalists interviewed

  9. NIH Director’s Pioneer Award 2005 Correlation Between Top 20 in Each Category

  10. 2005 NIH Director’s Pioneer Awardees http://nihroadmap.nih.gov/pioneer/Recipients05.aspx

  11. 2005 NIH Director’s Pioneer Awardees Pehr Harbury, Ph.D. Harbury plans to use his Pioneer Award to develop an approach called DNA Display as a means of engineering drugs significantly more quickly and cheaply than is currently possible.

  12. 2005 NIH Director’s Pioneer Awardees Erich Jarvis, Ph.D. Jarvis plans to use his Pioneer Award to test a hypothesis about the genetic machinery underlying vocal learning that could pave the way for repairing vocalization disorders in humans.

  13. 2005 NIH Director’s Pioneer Awardees Vicki Chandler, Ph.D. Chandler plans to use her Pioneer Award to search in humans for mechanisms similar to those she has characterized in plants, as these mechanisms could be associated with certain human diseases.

  14. NIH Director’s Pioneer Award 2006 • Program re-announced for FY2006 with minor modifications • Applications rather than nominations used • 3 letters of recommendation and single representative work submitted at time of application • More than 450 applications received • Single round of outside review performed • Interviews to be scheduled for August 2006

  15. NIH Director’s Pioneer Award • Short application concentrating on investigator, problem selected, evidence for innovation • Review conducted without careful matching of expertise of reviewers and applicants • Interviews provide evaluation of credibility that allows risk taking during review

  16. nihroadmap.nih.gov

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