1 / 5

Biomarkers HCLS F2F 2009-11-03

Biomarkers HCLS F2F 2009-11-03. Michael Miller. Gene Expression Biomarker Definition. A set of sequences/genes/transcripts identified via some sequence database (Entrez Gene, GenBank, Affymetrix,…) Each sequences’ expression value

malia
Télécharger la présentation

Biomarkers HCLS F2F 2009-11-03

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. BiomarkersHCLS F2F 2009-11-03 Michael Miller

  2. Gene Expression Biomarker Definition • A set of sequences/genes/transcripts identified via some sequence database (Entrez Gene, GenBank, Affymetrix,…) • Each sequences’ expression value • An algorithm that allows a new gene expression profile to be matched against the Biomarker and produces a score

  3. MammaPrint MammaPrint Figure 2 Nature 415, 530-536(31 January 2002) doi:10.1038/415530a

  4. GenSigDB • http://compbio.dfci.harvard.edu/genesigdb/ • Significant Gene Lists from PubMed Articles • Does not include signatures • Hosted by Dana Farber Cancer Institute

  5. Challenges • Gene Lists are embedded in articles • Often there is no clear algorithm included in articles to add new gene profiles

More Related