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This study by Stewart et al. (2011) explores the intratumoral heterogeneity of carbonic anhydrase IX (CAIX) expression in renal cell carcinoma using automated quantitative analysis. The findings underscore the significance of molecular pathology in understanding tumor behavior and tailoring management strategies for renal cell carcinoma. The research highlights how variations in CAIX expression may influence tumor characteristics and treatment response, providing insights into personalized medicine approaches for cancer management.
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Figure 1 Intratumoral heterogeneity of carbonic anhydrase IX (CAIX) expression (red signal) in renal cell carcinoma, by automated quantitative analysis Stewart, G. D. et al.(2011) What can molecular pathology contribute to the management of renal cell carcinoma? Nat. Rev. Urol. doi:10.1038/nrurol.2011.43