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This study investigates the ectopic expression of two actin isoforms, 64 kDa and 43 kDa, in the HPKIA and HPKII models. Using SORBS2 and pCDH vectors, we analyze the impact of these actins on cellular dynamics and function. The findings highlight the significance of ectopic actin isoforms in cellular signaling and structure, potentially contributing to further understanding of actin-related diseases. This research adds valuable insights to the fields of molecular biology and cellular biophysics, opening avenues for therapeutic exploration.
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HPKIA HPKII (A) (B) SORBS2 SORBS2 pCDH pCDH (C) ectopic expression ectopic expression 64 kDa 64 kDa actin actin 43 kDa 43 kDa