European Technology Platform for Global Animal Health (ETPGAH)

1. European Technology Platform for Global Animal Health (ETPGAH) Danish Mirror Group Ideas to be transformed into research projects Copenhagen 8 September 2009 Jim Scudamore

2. Ideas to be transformed into research projects Outline of the Presentation. • Introduction • The Action Plan • Danish Proposals • Funding of Proposals • Conclusions

3. ETP Global Animal HealthThe Vision To facilitate and accelerate the development and distribution of the most effective tools for controlling animal diseases of major importance to Europe and the rest of the world, thereby improving human and animal health, food safety and quality, animal welfare, and market access, contributing to achieving the Millennium Development Goals.” Published August 2005

4. ETP Global Animal HealthThe Strategic Research Agenda The SRA is the mechanism to deliver the vision. SRA has 2 overarching objectives:- • to deliver new and improved tools for the control of major diseases and • to deliver the 61 recommendations within the 6 themes of the SRA which in turn will facilitate the development and delivery of new tools Published May 2006

5. ETP Global Animal HealthAction plan • 61 Recommendations • Proposals concerning what needs to be done • Action Plan is much more specific • Designed to be converted into research or information gathering initiatives Published July 2007

6. ETP Global Animal HealthAction plan The Action Plan is intended to be a flexible working document, subject to regular review and up dating by the ETPGAH to ensure that the SRA is on target and that the recommendations are being delivered. Published July 2007

7. ETP Global Animal HealthThe Process DISCONTOOL 2008 Stakeholders, led by industry, come together to agree on a common vision for the technology Stakeholders, define a Strategic Research Agenda setting the necessary mid- to longterm objectives Stakeholders, implement the Strategic Research Agenda with the mobilisation of significant human and financial resources EMIDA 2008 ICONZ 2009 Vision paper: “EU TP Global Animal Health” Launch Dec 2004 Final version August 2005 Strategic Research Agenda: Published May 2006 Action Plan: Published July 2007 Examples from FP7

8. Ideas to be transformed into research projects Outline of the Presentation. • Introduction • The ETPGAH Action Plan • Danish Proposals • Funding of Proposals • Conclusions

9. ETP Global Animal HealthAction plan • Chapter 2 details the actions to implement the 61 recommendations of the SRA using a standard format for consistency

10. ETP Global Animal HealthAction plan • Contents of the plan • Chapter 2 • Themes & Recommendations within themes • Detailed Proposals 4 Enabling factors 17 5 Regulatory & Societal Issues 8 1 Prioritise animal diseases and infections 8 3 Fundamental Science 5 6 Global Perspective 5 2 Gap Analysis 8 Action plan Finalised and submitted to the EU Commission in July 2007

11. ETP Global Animal HealthAction plan • Chapter 3 Deals with the research requirements for the priority diseases specifically dealing with prioritisation and gap analysis

12. ETP Global Animal HealthAction plan • Annex 1 Tasks for the European Centre for Epidemiology and Infectious animal disease • Annex 2 – Categories of Disease • Annex 3 – Prioritisation Model • Annex 4 – Bluetongue Disease Information • Annex 5 – Bluetongue Gap Analysis

13. ETP Global Animal HealthAction Plan How will the action plan be used. Template Guidance Liaison Lobbying Funding

14. ETP Global Animal HealthAction Plan The Action plan serves to provide an input for:- • Future EC Framework Programmes which will involve close cooperation with EC, Member States and European Parliament representatives. • Future national research programmes where it will provide better opportunities to align and coordinate national programmes • Public/private research partnerships exploring ways to develop an integrated approach to developing new tools to control animal diseases. • Industry which has an important role working in partnership to develop new products, which can be delivered in the field.

15. Ideas to be transformed into research projects Outline of the Presentation. • Introduction • The Action Plan • Danish Proposals • Funding of Proposals • Conclusions

16. Proposals A European Academic Network for Vaccine Research Coordination of Veterinary Epidemiological Research on Infectious Diseases in Europe Endemic diseases Questions What is new? How do these proposals fit into the action plan? What are the priority diseases? What is an endemic disease? What benefits would they bring? What is the best way forward? ETP Global Animal HealthDanish Proposals and the Action Plan

17. A European Academic Network for Vaccine Research. Objectives: • To promote the development of vaccines for endemic diseases including MUMS Deliverables • To support all aspects of design, development and testing of vaccines and strengthen collaboration (AP3.1) • To train young researchers. (AP 4.5) • To advise and propose strategies for future research of more generic and fundamental nature in all aspects of vaccine development.(AP4.3) • To provide information, advice and decision support to European authorities. • To identify the main problems related to vaccine research from the perspective of all stakeholders • To identify global centres of excellence • To identify subjects and areas of importance in relation to innate immunity, T-cell immunity, DNA vaccines, Bio-informatics, antigen delivery systems.(AP3.3). Genomic and proteomic approach

18. Coordination of Veterinary Epidemiological Research on Infectious Diseases in Europe (1) Objectives: • To ensure the coordination of research and education activities in the area of veterinary epidemiology of infectious diseases. Deliverables • To create a cost effective body to coordinate animal health research at a European level. • To act as a coordination body for epidemiology in the EU • To train young researchers. (AP 4.5) • To initiate timely projects related to veterinary epidemiological research into infectious diseases. • To provide objective, transparent, and comparable information concerning the occurrence, dissemination and control of animal diseases. • To provide easy access to new animal health research concerning risk based and targeted surveillance • To develop risk based principles to optimise the use of resources • To contribute through horizon scanning to an updated picture of the threats as regards animal diseases. • To contribute to the Community Animal Health plan

19. Coordination of Veterinary Epidemiological Research on Infectious Diseases in Europe (2) Deliverables • To initiate multinational harmonised data collection, epidemiological studies and reporting of trans border diseases outbreaks • To develop and use modelling for animal diseases and surveillance to promote scenarios for the control including cost benefit of potential control measures. • To initiate research in sampling and survey methodologies including risk based principles in disease monitoring or surveillance in order to secure a more focused use of resources • To identify challenges including animal heath questions related to climate change to ensure European preparedness.

20. ETP Global Animal HealthAction Plan 3.2. Establish a European Centre for Epidemiology and Infectious Animal Diseases. SRA Recommendations. 21 Objective: In Europe, epidemiological research is carried out in national institutions and is mainly organised and funded by the EU Member States. A central institution with coordinating responsibilities for fundamental and applied research in the field of infectious diseases and epidemiology is required. In view of the recent enlargement of the EU there is a requirement for an efficient infrastructure or centralised institution for fundamental and applied research into epidemiology and infectious diseases. Deliverables: • A scoping study of the options available for improving applied research into epidemiology and infectious diseases and the development of an appropriate infrastructure with responsibility for training epidemiologists to create a critical mass for the future • A report into the pros and cons of a virtual versus a physical centre • The implementation of the most appropriate option either the establishment of a specific or a virtual European Central Institution for Epidemiology and Animal Infectious Diseases. Alternatively a fully funded community reference laboratory could be established. The centre to act as a repository for a range of databases on disease information. • Availability of a budget for the centre whether virtual or physical

21. ETP Global Animal HealthAction Plan Tasks for European Centre for Epidemiology and Infectious Animal Disease • Development of knowledge along the entire animal health chain, e.g.:- research in the area of interaction between epidemiology and infection biology focussed on the development of integrated control strategies;- integration of innovation by research groups with development of vaccines and diagnostics by the pharmaceutical industry; - policy support of governmental bodies in the fields of prevention and control. • Development of risk assessment models • Data mining techniques to be developed and implemented • Reference Centre for education and training, particularly in the field of epidemiology. • Integration of research with research centres for human infectious diseases. • Management of a common European database for surveillance and early warning. • Initiation of joint research programmes and exchange of expertise with centres in developing countries, in particular the source countries for (re)emerging infectious diseases (i.e. twinning)

22. ETP Global Animal HealthDanish Proposals and the Action Plan Endemic diseases. Objective • To develop a broader scientific approach to welfare threatening diseases Deliverables • Multidisciplinary approach to causes and best intervention strategies • Explore links between immunity development, pathogenesis and epidemiology to areas such as business and animal health economics, animal ethics and sociology • Explore from the welfare perspective as opposed to production perspective • Define welfare spanning farmer and consumer

23. ETP Global Animal HealthDanish Proposals and the Action Plan Diseases in the Action plan. In the Action plan the process was developed further with the result that 47 priority diseases in 3 groups were listed. Group 1 Epizootic diseases and diseases for surveillance Group 2 : Zoonoses and food-borne diseases Group 3: Major food-producing animal disease complexes

24. FP7 projects contributing to research

26. FP6 and FP7 projects contributing to research

27. ETP Global Animal HealthAction Plan

28. Ideas to be transformed into research projects Outline of the Presentation. • Introduction • The Action Plan • Danish Proposals • Funding of Proposals • Conclusions

29. ETP Global Animal HealthAction plan: Funding Sources of funding for the proposals EC Programs (e.g. FP7, COST, DGs) • Close consultation with EC, MSs, EP representatives National research programs- EMIDA • Providing opportunities to better align and coordinate national programs. (EMIDA ERA-Net), SCAR Public/private research partnerships • Exploring areas of strategic importance in which ambitious initiatives can be taken Charities and private non-profit foundations . All these funding bodies have their own agendas/priorities that are set independently of each other)

30. EC Funding :Framework 7 Programme 2007 to 2013 Cooperation – Collaborative research €32.342b (€1.944) Ideas – Frontier Research €7.460b People – Human Potential €4.728b Capacities – Research Capacity €4.243b • Cooperation is 64% of budget of FP 7 budget of €50.524 billion • Food, Agriculture & Biotech - €1.944b

31. Cooperation – Collaborative research Joint Technology Initiatives Collaborative research (Collaborative projects; Networks of Excellence; Coordination/support actions) Coordination of non-Community research programmes (ERA-NET; ERA-NET+; Article 169) International Cooperation Small collaborative projects (“small or medium-scale focused research actions”) are projects with a requested Commission contribution up to € 3 million Large collaborative projects (“large-scale integrating projects”) and Networks of Excellence between € 3 million and € 6 million Coordination and Support Actions (CSA) up to € 1 million

32. Cooperation – Collaborative research Calls made Call FP7-KBBE-2007-1: Publication Date: 22/12/2006: Deadline: 02/5/07 ERA Net, discontools, BTb, ASF, RVF, WNF, CCF FP7- KBBE-2007-2A: Publication Date: 15/6/2007, Deadlines: 11/9/07 : stage 2 19/2/08 - Stage 2 (only for proposals retained at stage 1 Wildlife, ICONZ, zoonoses FP7- KBBE-2008-2B: Publication Date: 30/11/ 2007: Deadline: 26/2/ 2008. FMD, CSF FP7- KBBE-2009-3: Publication Date: 03/9/2008 : Deadline: 15/1/ 2009 PRRS, Orboviruses, Tick borne diseases, campylobacter FP7-KBBE-2010-4 Publication Date 30/7/2009 Deadline 14/1/2010 Swine influenza, Parasites,welfare

33. FP7 KBBE-2010-4

34. EC Funding :Framework 7 Programme 2007 to 2013 : Cooperation – Collaborative research €32.342b (€1.944) Ideas – Frontier Research €7.460b People – Human Potential €4.728b Capacities – Research Capacity €4.243b • Cooperation is 64% of budget of FP 7 budget of €50.524 billion • Food, Agriculture & Biotech - €1.944b

35. 1. Research Infrastructures 2. Research for the benefit of SMEs 3. Regions of Knowledge 4. Research Potential 5. Science in Society 6. Activities of International Cooperation Capacities – Research Capacity

36. EC Funding : COST Programme • COST – together with EUREKA and the EU framework programmes – is one of the three pillars of joint European research initiatives. These three complementary structures have differing areas of research.

42. EC Funding :Framework 7 Programme 2007 to 2013 : • The ERA-NET scheme was introduced under FP6 to support the networking of research funding organisations (programme owners and managers e.g. government ministries and research councils) to develop and strengthen the coordination of national research programmes. • KBBE-2007-1-3-02: Coordination of European research in the area of animal health, including emerging threats, infectious diseases and surveillance. ERA-Net (SRA 13,35,37,47) (1m€) 3 years 1/4/08

43. Member State Funding: EMIDA ERA-NET • Coordination of European research in the area of animal health, including emerging threats, infectious diseases and surveillance • 26 partners in 19 countries and four associated partners • Combined research budget in the region of 270 million Euros

45. Aims of EMIDA The overall aim of the Animal Health ERA-NET is to build on and accelerate the work of the SCAR CWG in developing a durable focused network of national research funders in Member and Associated States of the EU for the purpose of sharing information, coordinating activities and working towards a common research agenda and mutual research funding activities in the field of animal health.

46. Scope of EMIDA The scope of the project will include emerging and major infectious diseases of production animals, including fish and bees and including those conditions which pose a threat to human health but excluding food safety issues relating to livestock products and diseases of wildlife, except where they act as a reservoir of infection for humans and animals.

48. Transnational Calls from EMIDA Vectorborne diseases - Development of underpinning knowledge and tools for early warning, detection & monitoring and novel control strategies Zoonoses and antimicrobial resistance, excluding microbial safety of products - Development of underpinningknowledge and tools for early warning, detection & monitoring and novel control strategies Major infectious diseases affecting productionDevelopment of underpinning knowledge and tools for early warning, detection & monitoring and novel control strategies, including genetics of resistance Aquaculture - Development of underpinning knowledge and tools for early warning, detection & monitoring and novel control strategies, particularly vaccine-based approaches

49. Transnational Calls from EMIDA Pre-announcement flyer www.EMIDA-ERA.NET Formal Announcement 21 July Call opens 7 September Pre-proposal Submission deadline 16 November Invitation for full proposals 23 December Deadline for full proposals 1 March Funding decisions June 2010

50. Ideas to be transformed into research projects Outline of the Presentation. • Introduction • The Action Plan • Danish Proposals • Funding of Proposals • Conclusions