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Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion

Computer No. 87. ISMRM 2014 E-Poster #4306. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion . J. Su 1 , T. Tourdias 2 , M.Saranathan 1 , and B.K .Rutt 1 1 Department of Radiology, Stanford University, Stanford, CA, United States

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Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion

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  1. Computer No. 87 ISMRM 2014 E-Poster #4306 Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion J.Su1, T. Tourdias2, M.Saranathan1, and B.K.Rutt1 1Department of Radiology, Stanford University, Stanford, CA, United States 2Department of Neuroradiology, Bordeaux University Hospital, Bordeaux, France WMnMPRAGE template of 17 subjects at 1mm3 Automatic segmentations (filled region) for whole thalamus and nuclei with the manual truth (yellow outline) overlaid in an MS patient.

  2. ISMRM 2014 E-Poster #4306 Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion J.Su1, T. Tourdias2, M.Saranathan1, and B.K.Rutt1 1Department of Radiology, Stanford University, Stanford, CA, United States 1Department of Neuroradiology, Bordeaux University Hospital, Bordeaux, France Declaration of Conflict of Interest or Relationship I have no conflicts of interest to disclose with regard to the subject matter of this presentation.

  3. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Background Manual segmentation of thalamic nuclei from WMnMPRAGE acquisition from a normal control. 1Tourdias et al. Neuroimage. 2013 Sep 7;84C:534-545. 2Niemann et al. Neuroimage. 2000 Dec;12(6):601-16.

  4. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Purpose

  5. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Scanning Methods Fully Sampled 16min Accelerated 5.5min

  6. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Processing Methods: Registration An axial slice from the 1mm isotropic resolution WMnMPRAGE template formed by averaging over 17 subjects

  7. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Background: Label Fusion Differing Opinions Trust Estimate t1 Output t2 t3 · · · tN 3Cardoso et al. Med Image Anal. 2013 Aug;17(6):671-84.4Warfield et al. IEEE Trans Med Imaging. 2004 Jul;23(7):903-21.

  8. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Processing Methods: STEPS Optimization Pul MTT

  9. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Results Performance of the algorithm compared to a previous multi-modal technique 5Stough et al. Proc IEEE IntSymp Biomed Imaging. 2013:852-855.

  10. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Results 1Tourdias et al. Neuroimage. 2013 Sep 7;84C:534-545.

  11. Automatic Segmentation of Thalamic Nuclei with STEPS Label Fusion ISMRM 2014 #4306 Discussion & Conclusions 6Yushkevichet al. Neuroimage. 2010 Dec;53(4):1208-24. [Cite MICCAI winners]

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