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DYSPEPSIA. Dyspepsia. Implies chronic GORD IBS Ulcers Gall Stones Cancer ‘Functional’. Dyspepsia. Perspective 10% of all GP consultations 9,000 endoscopies per year at Walsgrave, waiting time up to 9 months Pragmatism in treatment and algorrhythms. Dyspepsia. GORD Heartburn
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Dyspepsia Implies chronic • GORD • IBS • Ulcers • Gall Stones • Cancer • ‘Functional’
Dyspepsia Perspective • 10% of all GP consultations • 9,000 endoscopies per year at Walsgrave, waiting time up to 9 months • Pragmatism in treatment and algorrhythms
Dyspepsia GORD • Heartburn • Waterbrash • Volume reflux • Response to PPIs • Dysphagia Diagnosis?? Management
Laparoscopic Fundoplication Normal Subject
Laparoscopic Fundoplication 24 hour trace of severe GOR
Laparoscopic Fundoplication Interpretation of 24h tape of severe GOR
Dyspepsia IBS • Abdominal pain - sites • Bloating • Distension • Variable bowel habit • Relation to stress How to talk to them!
Dyspepsia Ulcers DUs - • Foregut • Nature of pain • The 3 best features of history … GUs …. The two big causes • Treatment • Remember NSAIDs
Dyspepsia Gall Stones • SEVERE foregut pain • duration • distribution • vomiting • recovery Other vague symptoms .......
Dyspepsia Cancer • ‘New’ dyspepsia • Cancer age group • ‘Alarm’ symptoms • or signs • Dilemma Surgery?? Results??
Common dyspeptic cancers • Oesophagus • Stomach • Pancreas • Liver mets 16
Dyspepsia ‘Functional’ • Upper abdominal pain • Investigations negative • Relation to food, stress • Vomiting unusual
Investigation (The conventional sequence) But really what is the question • Cancer?? Or reassurance • Cause of dyspepsia • Helicobacter status • Does it really matter?? - answer Or just treat and see?? • What conditions not
WHICH INVESTIGATION? • -INVESTIGATION • ENDOSCOPY • BARIUM SWALLOW • CT • MANOMETRY • OESOPHAGEAL Ph • PPI TEST • QUESTION • MUCOSA / THERAPEUTICS • ANATOMY / FUNCTION • MOTILITY • FUNCTION / REFLUX
DYSPEPSIA Implies chronic GORD IBS Ulcers Gall Stones Cancer ‘Functional’ Implies chronic GORD IBS Ulcers Gall Stones Cancer ‘Functional’ (Alcoholic gastropathy)