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By Gucci Aguh Shannon Murphy

STRONGLYLOIDES STERCORALIS. By Gucci Aguh Shannon Murphy. Introduction. Strongyloides stercoralis  is a common enteric helminthic parasite “Thread worm” Parasite of man. 38 Species found in dogs, cats and many other mammals 2 different life cycle forms Free-living Parasytic.

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By Gucci Aguh Shannon Murphy

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  1. STRONGLYLOIDESSTERCORALIS By Gucci Aguh Shannon Murphy

  2. Introduction • Strongyloides stercoralis is a common enteric helminthicparasite • “Thread worm” Parasite of man • 38 Species found in dogs, cats and many other mammals • 2 different life cycle forms • Free-living • Parasytic

  3. Who gets it? Where? • The Definitive host of Stronglyloides Stercoralis is Humans • S. Fulleboni infects Chimpanzees and Baboons • Geographic Distribution • Tropical and Subtropical Areas • Cases also occur in temperate zones • Most frequently found in rural areas, Insitutional settings and lower socioeconomic groups

  4. Morphology • Adult females measure 2-3 mm in length by 20 to 50 μm. • Long cylindrical Esophagus which occupies 1/3 the length of the worm. • Rhabditiod is (L-1 stage) 180 – 380 by 14-20 μm. • Rhabditoid larvae have a short buccal cavity, an attenuated tail and a prominent genital in its early stage. 
These features are used to differentiate S. stercoralis from Hookworm rhabditiod larvae.

  5. Morphology • Filariform larvae (L3, the infective stage) have a long non bulbous esophagus 
of about 2/5 of the lenght of the body. • Filariform larvae are slender and have a notched tip of the tail. • Filariform larvae measure 300-600 µm in lenght by 10-20 µm.

  6. Life Cycle

  7. RhabditiodEosophagus Filariform larvae have a long non bulbous esophagus 


  8. The intestinal mucosa during S.stercoralishyperinfection: a d b c e The intestinal mucosa during S.stercoralishyperinfection: 
a) histological section of the mucosa showing an adult worm, larvae and eggs; 
b) at higher magnification larvae and eggs within the mucosa; 
c) cross section of an adult female in the crypt: 2 reproductive tubes 
and the intestine are visible; 
d) egg (50-60 by 30-35 µm) of S.stercoralis within the mucosa; 
e) longitudinal section of an adult female showing a reproductive tube the intestine. 


  9. b a c d The free living females measure about 1 mm in lenght by 50-75 µm: 
a) a free living female containing embryonated eggs; 
b) the free living females have a rhabdithoid esophagus; 
c) particular of the buccal cavity; 
d) the rhabdithoid esophagus; 
e) eggs within the free-living female. 
 e

  10. Pathogenesis • Frequently is Asymptomatic • GI Symptoms • Abdominal Pain and Diarrhea • Pulmonary symptoms can occur • Dermatological symptoms • Uticarial Rashes in Buttocks and waist area • Immunocompromised patients • Abdominal Pain, Distension, shock, pulmonary and neurological complications with septicemia and is potentially fatal.

  11. Diagnosis • Larvae in stool using concentration methods. • Filter paper technique and wet mount preparation. • larvae in duodenal fluid. • Serial Samples. • Antibody detection. • Morphological comparison to other parasites.

  12. Treatment & Prevention • Anthelmintics • Ivermectine (200 micrograms/Kg in a single dose) • Albendazole (25 mg/Kg twice a day for 2 days) • Prevention • Teaching sanitation • Proper disposal of human waste

  13. References • http://www.dpd.cdc.gov/dpdx/html/Strongyloidiasis.htm Center for Disease Control and Prevention • http://www.diagnose-me.com/cond/C654193.html • Strongyloides Stercoralis. http://www.cdfound.to.it/html/str1.htm#ss0

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