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Analysis of Protein Scores and Peptide Rankings in ALS Research

This document presents a detailed analysis of peptide scores and rankings related to amyotrophic lateral sclerosis (ALS) as found in the supplementary data from Pasinetti et al. Key findings include specific scores for peptides such as ASNDMYHSR and ALDFAVGEY, along with their corresponding significant values. The implications of these rankings on ALS research are explored, highlighting the relevance of such peptides in the development of potential therapies and understanding disease mechanisms. Further visual data representations, including figures, illustrate the results.

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Analysis of Protein Scores and Peptide Rankings in ALS Research

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  1. MAGPLRAPLL LLAILAVALA VSPAAGSSPG KPPR LVGGPM DASVEEEGVR R ALDFAVGEY NKASNDMYHS R ALQVVRARK LVGGP M DASVEEEGVR QIVAGVNYFL DVELGRTTCT KTQPNLDNCP FHDQPHLKRK AFCSFQIYAV PWQGTMTLSK STCQDA figure 1 (Pasinetti et al., Online Supplement Data) A B MW Ctl ALS C Score Expect Rank Peptide 52 0.0023 1 ASNDMYHSR 50 0.0041 1 ALDFAVGEYNK 78 9.5e - 006 1 LVGGP M DASVEEEGVR D

  2. figure 2 (Pasinetti et al., Online Supplement Data) E

  3. figure 3 (Pasinetti et al., Online Supplement Data) *

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