Stress-Related Disorders

Stress-Related Disorders DR. JAWAHER A. AL-NOUH Consultant psychiatrist-clinical assistant professor -department of psychiatry K.S.U-K.K.U.H

Objectives: -What is stress? .-Reaction to stress: normal and pathological. -Grief. Adjustment disorders. -Acute stress disorder. -Post traumatic stress disorder( PTSD).

“…a sociopsychophysiologicalphenomenon. It is a composite of intellectual, behavioral, metabolic, immune, and other physiological responses to a stressor (or stressors) of endogenous or exogenous origins. The stressors may involve thoughts and feelings or may be a perceived threat or some other condition such as cold. The response generally serves a protective, adaptive function. Lindsay, Carrieri-Kohlman,

Stress • “….stress is the nonspecific response of the body to any demand, whether it is caused by, or results in pleasant or unpleasant conditions.” • Hans Selye, MD

Types of Stressors Career Pressures

Adjustment Disorders • The adjustment disorders: emotional response to a stressful event. • the stressor involves financial issues, a medical illness, or a relationship problem. • the symptoms must begin within 3 months of the stressor. • It can be :acute(6monthes)or chronic(more than 6monthes)

Epidemiology • can occur at any age, but are most frequently diagnosed in adolescents. • common precipitating stresses: school problems, parental rejection and divorce, and substance abuse, marital problems, divorce, moving to a new environment, and financial problems. • one of the most common psychiatric diagnoses for disorders of patients hospitalized for medical and surgical problems. • from 2 to 8 percent of the general population.

DSM-IV-TR Diagnostic Criteria for Adjustment Disorders • A The development of emotional or behavioral symptoms in response to an identifiable stressor(s) occurring within 3 months of the onset of the stressor(s). • B These symptoms or behaviors are clinically significant as evidenced by either of the following: • marked distress that is in excess of what would be expected from exposure to the stressor • significant impairment in social or occupational (academic) functioning • C The stress-related disturbance does not meet the criteria for another specific Axis I disorder and is not merely an exacerbation of a preexisting Axis I or Axis II disorder. • D The symptoms do not represent bereavement. • E Once the stressor (or its consequences) has terminated, the symptoms do not persist for more than an additional 6 months.

Specifyif: • Acute: if the disturbance lasts less than 6 months. • Chronic: if the disturbance lasts for 6 months or longer.

Adjustment disorders are coded based on the subtype • selected according to the predominant symptoms. • 1-With depressed mood(low mood, tearfulness)2-With anxiety ( agitation. fearfulness)3-With mixed anxiety and depressed mood • (mainly in adults)4-With disturbance of conduct( in adolescents)5-With mixed disturbance of emotions and conduct6-Unspecified: • -in children and the elderly: physical symptoms

CourseandPrognosis: • With appropriate treatment, the overall prognosis of an adjustment disorder is generally favorable. • Most patients return to their previous level of functioning within 3 months. • Some persons (particularly adolescents) who receive a diagnosis of an adjustment disorder later have mood disorders or substance-related disorders. Adolescents usually require a longer time to recover than adults.

DifferentialDiagnosis • MDD. • Acute stress disorder and PTSD .

Treatment:

Summary of ADJ.DIS.

Acute stress disorder and PTSD • The stressors are sufficiently overwhelming to affect almost anyone. • arise from experiences in war, torture, natural catastrophes, assault, rape, and serious accidents, for example, in cars and in burning buildings.

*a: • The person has been exposed to a traumatic event in which both of the following were present: • the person experienced, witnessed, or was confronted with an event or events that involved actual or threatened death or serious injury, or a threat to the physical integrity of self or others • the person's response involved intense fear, helplessness, or horror.Note: In children, this may be expressed instead by disorganized or agitated behavior.

B: • The traumatic event is persistently re-experienced in one (or more) of the following ways: • recurrent and intrusive distressing recollections of the event, including images, thoughts, or perceptions. Note: In young children, repetitive play may occur in which themes or aspects of the trauma are expressed. • recurrent distressing dreams of the event. Note: In children, there may be frightening dreams without recognizable content. • acting or feeling as if the traumatic event were recurring (includes a sense of reliving the experience, illusions, hallucinations, and dissociative flashback episodes, including those that occur on awakening or when intoxicated). Note: In young children, trauma-specific reenactment may occur. • intense psychological distress at exposure to internal or external cues that symbolize or resemble an aspect of the traumatic event • physiological reactivity on exposure to internal or external cues that symbolize or resemble an aspect of the traumatic event

C:- • Persistent avoidance of stimuli associated with the trauma and numbing of general responsiveness (not present before the trauma), as indicated by three (or more) of the following: • efforts to avoid thoughts, feelings, or conversations associated with the trauma • efforts to avoid activities, places, or people that arouse recollections of the trauma • inability to recall an important aspect of the trauma • markedly diminished interest or participation in significant activities • feeling of detachment or estrangement from others • restricted range of affect (e.g., unable to have loving feelings) • sense of a foreshortened future (e.g., does not expect to have a career, marriage, children, or a normal life span)

D Persistent symptoms of increased arousal (not present before the trauma), as indicated by two (or more) of the following: • difficulty falling or staying asleep • irritability or outbursts of anger • difficulty concentrating • hyper vigilance • exaggerated startle response • FThe disturbance causes clinically significant distress or impairment in social, occupational, or other important areas of functioning.

Onset:

Duration:

Summary of the diagnosis: • Re-experiencing, • avoidance, • hyper arousal.

Differential Diagnosis: • R/O organic disorders • head injury during the trauma. • Epilepsy • alcohol-use disorders • other substance-related disorders (Acute intoxication or withdrawal) • panic disorder and generalized anxiety disorder • Major depression is also a frequent concomitant of PTSD. • borderline personality disorder, dissociative disorders, and factitious disorders.

epidemiology : • the lifetime prevalence: • 8 % of the general population. • Risk Factors:single, divorced, widowed, socially withdrawn, or of low socioeconomic level. • The most important risk factors • are the severity, duration, and proximity of a person's exposure to the actual trauma

Treatment:

Encouragement to discuss the event: support and reassurance • Pharmacotherapy: SSRI-BZD for short period. • Psychotherapy.

Comorbidity: • high rates • two thirds (66%) having at least two other disorders. • Common: • depressive disorders • substance-related disorders • other anxiety disorders • bipolar disorders

Prognosis • Symptoms can fluctuate over time and may be most intense during periods of stress. • Untreated, • about 30 percent of patients recover completely, • 40 percent continue to have mild symptoms, • 20 percent continue to have moderate symptoms, • 10 percent remain unchanged or become worse. • After 1 year, about 50 percent of patients will recover. • A good prognosis • rapid onset of the symptoms, • short duration of the symptoms (less than 6 months), • good pre-morbid functioning, • strong social supports • absence of other psych.disorder. medical, or substance-related disorders or other risk factors.

ASK:

Bereavement, Grief, and Mourning: • psychological reactions of those who survive a significant loss. • mourning is the process by which grief is resolved. • Bereavement literally means the state of being deprived of someone by death and refers to being in the state of mourning

stages of grief: • 1-Shock and denial (minutes, days, weeks) Disbelief and numbness and protest • 2-Acute distress (weeks, months) Waves of somatic distress Withdrawal Preoccupation Anger Guilt Lost patterns of conduct Restless and agitated Aimless and amotivational Identification with the bereaved

3-Resolution (months, years) Have grieved Return to work Resume old roles Acquire new rolesRe-experience pleasure Seek companionship and love of others

Pathological grief: • -Abnormally intense grief: MDD • -prolonged grief.>6 months • -Delayed grief : appear>2weeks after the death. • -Distorted grief. Unusual picture,e.g hostility. Over activity.

Normalreaction to impending death: • Stage 1: Shock and Denial(I feel fine) • Stage 2: Anger(why me?) • Stage 3: Bargaining (I will give any thing for more time) • Stage 4: Depression(nothing worked) • Stage 5: Acceptance (I cant fight it)

Helping the bereaved and dying patients • -1-facilitate normal process of grief. • 2-support • 3-consider practical problems • 4-medications

Bereavementordepression? • In bereavement : • NO morbid feelings of guilt and worthlessness, suicidal ideation, or psychomotor retardation. • Dysphoria often triggered by thoughts or reminders of the deceased. • Onset is within the first 2 months of bereavement. • Duration of depressive symptoms is less than 2 months. • Functional impairment is transient and mild. • No family or personal

Laughter and tears are both responses to frustration and exhaustion . . .I myself prefer to laugh, since there is less cleaning up to do afterward.” • -Kurt Vonnegut

Reference: • BASIC PSYCHIATRY by prof.m.Alsughayer • –second edition • Pages189-202

THANK YOU

Stress-Related Disorders