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Response and Adaptation of Cells to Injury

Response and Adaptation of Cells to Injury . What is Pathophysiology?. Terms and Definitions. Terms and Definitions: Patho. Terms and Definitions: Patho. Cellular Adaptations. Cells have mechanisms to adapt Minor alterations: ex: pregnancy Reversible tissue changes

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Response and Adaptation of Cells to Injury

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  1. Response and Adaptationof Cells to Injury What is Pathophysiology?

  2. Terms and Definitions

  3. Terms and Definitions: Patho

  4. Terms and Definitions: Patho

  5. Cellular Adaptations • Cells have mechanisms to adapt • Minor alterations: ex: pregnancy • Reversible tissue changes • Irreversible tissue changes

  6. Terms Used for Cell Changes

  7. Abnormal Cellular Growth Patterns

  8. Examples

  9. Cell Damage and Necrosis • How may cells be damaged? • In the body: ischemia, physical agents, mechanical damage, foreign substances, microorganisms, abnormal metabolites, nutritional deficits, fluid & electrolyte imbalance

  10. Major causes of hypoxia-anoxia

  11. Cell Damage and Necrosis • Two Stages • Initial cell damage causes alteration in a metabolic reaction, which leads to • Loss of function of the cell • If the factor causing the damage is removed quickly, the cell may be able to return to normal (reversible) • If the noxious factor stays, the damage becomes irreversible, and the cell dies

  12. Prevention of Disease • Choose to be a non-smoker & avoid second-hand smoke • Choose a variety of low-fat , high fiber foods. Maintain a healthy body weight and limit alcohol intake. • Protect yourself & your family from the sun. • Regularly schedule Pap tests & mammograms according to age. Practice monthly BSE, TSE. • See your doctor/dentist regularly. • Be aware of changes in your normal state of health. • Be aware if changes in your normal state of health. If you discover a lump or mole that has changed, or sore that won’t heal, have it checked. • At home and work, follow health & safety instructions when using hazardous materials.

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