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Overview of Mass Analyzers and Spectrometers: Types and Applications

This comprehensive guide covers various types of mass analyzers including Magnetic Sector Instruments, Quadrupole (QUADS), Ion Trap (TRAPS), Time-of-Flight (TOFs), and Fourier Transform Ion Cyclotron Resonance (FT-ICR). We explore their principles of operation, stability diagrams, and applications in mass spectrometry, such as MALDI and SIMS for biological tissues. The document offers insights into different scanning modes and the dynamics within quadrupole systems, enhancing understanding of modern mass spectrometry techniques.

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Overview of Mass Analyzers and Spectrometers: Types and Applications

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  1. Mass Analysators

  2. Types of Spectrometers Magnetic Sector Instruments Quadrupole Instrum [QUADS] Ion Trap [TRAPS] Time-of -Flight Instr. [TOF`s] Fourier Transform Ion Cyclotron Resonance [FT-ICR`s]

  3. ION TRAP

  4. Stability Diagram for Commercial Traps

  5. Stability Diagram for Commercial Traps LTQ ION TRAP

  6. 1.Auskopplung

  7. 2.Auskopplung

  8. Scan-Modi eines TSQs F1 F2 F3 F21 F22 F23 M+ M+ etc Prod.ionen Scan F1 F2 F3 F21 F22 F23 FX+ M+ Parent Scan M+ etc F1 F2 F3 F21 F22 F23 M+ (M- X)+ Neutral Loss Scan M+ etc M+ (M+ X)+ Neutral Gain Scan M+ + X (M+ X)+ Q 2 Stoßzelle Q 3 Q 1

  9. Dynode Turbo Q3 Q2 Q1 Q0 Inside the TSQ Quantum API

  10. TOF - MS

  11. Time of Flight Mass Spec

  12. Reflectron - TOF

  13. Time-of-Flight Mass Spectrometry • There are actually two type of mass analyzers in use for MALDI: • Reflectron time-of-flight mass spectrometer • Linear time-of-flight mass spectrometer

  14. SIMS of biol tissue; AC September 1, 1997

  15. ICR-FT-MS

  16. Motion of a charged particle in a magnetic field

  17. Ion cyclotron resonance phenomenon

  18. Ion cyclotron resonance phenomenon

  19. Ion cyclotron resonance phenomenon

  20. Detection of image current

  21. ICR-FT-MS

  22. Fourier Transform Spectrometers

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