1 / 27

TUMORACIÓN MAMARIA

TUMORACIÓN MAMARIA. B. Ocaña Castillo; A. Martínez Torrano; P. Blasco Muñoz; F. Martínez Díaz; F. Pastor Quirante; G. Ortuño Pacheco (H.G.U. Reina Sofía, Murcia) . HISTORIA CLÍNICA. Mujer 86 años

merlin
Télécharger la présentation

TUMORACIÓN MAMARIA

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. TUMORACIÓN MAMARIA B. Ocaña Castillo; A. Martínez Torrano; P. Blasco Muñoz; F. Martínez Díaz; F. Pastor Quirante; G. Ortuño Pacheco (H.G.U. Reina Sofía, Murcia)

  2. HISTORIA CLÍNICA • Mujer 86 años • AP: HTA; insuficiencia cardiaca; 2 cateterismos; 3 stent; insuficiencia renal; ooforectomizada; operada de glaucoma y cataratas • Enfermedad actual: tumoración mamaria (CSE) de 6cm de 1 año de evolución que crece progresivamente

  3. citoqueratina

  4. DIAGNÓSTICO METÁSTASIS DE MELANOMA

  5. TUMORES METASTÁSICOS EN LA MAMA • Mtx a mama desde tumores extramamarios raras • Infancia: RMS embrionario • Adultos: leucemia/linfoma/MM/carcinoma • Incidencia: 2% • 40% primera manifestación

  6. Nódulos solitarios, CSE, superficiales. Gg axilares + (25-80%). Unilaterales • Pruebas de imagen: circunscritas, no calcificadas. Av indistinguibles de 1º mama • Localización 1º: PTS Y MMSS (vía linfática) • Impt buena correlación cx-rx y sospecha: aspecto inusual para 1º mama/ausencia componente in situ/características típicas de o: primario: pigmento/ inclusiones intranucleares) • IHQ: S-100 (S:> 95%). CA mama 60% HMB-45 y Melan A: S: 70% Citoqueratinas – (av expresión aberrante de CAM5.5 y EMA)

  7. Tto y evolución diferente • Muerte 1º año desde dco • Pronóstico dep de sitio 1º y tipo histológico

  8. BIBLIOGRAFIA • O´malley FP, Pinder SE. Metastasic Tumors in “Breast Pathology”. Foundations in Diagnostic Pathology Series. Churchill Livingstone. Elsevier. China 2006. Pp 297-301, 311. • Tavassoli Fa, Devillee P (Eds): World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. IARC Press: Lyon 2003.Pags. 109;112 • Smyrniotis V, Theodosopoulos Th, Marinis A, Goula K, • Pshychogios J, Kondi-Pafiti a. Metastastic Disease in the • Breast From Nonmammary Neoplasm. Eur Gynaecol • Oncol.2005;26(5):547-50.

  9. •Noguera JJ, Martinez-Miravete R, Idoate F, Diaz L,Pina L,Zornoza G. Metastasis to the Breast: a Review of 33 Cases.Australasian Radiology 2007;51:133-138. •Lee AHS.The Histological Diagnosis of Metastases to thebreast from xtramammary Malignancies. J Clin Pathol2007; 60:1333-1341. • •Loffeld A. Marsden JR.Management of Melanoma • Metastasis to the Breast: Case Series and Review of theLiterature. Br J Dermat 2005; 152:1206-1210.

  10. •Loffeld A. Marsden JR.Management of Melanoma Metastasis to the Breast: Case Series and Review of the Literature. Br J Dermat 2005; 152:1206-1210. •Kurul S,Tas F, Büyükbabani N, Mudum A, Baykal C, Camlica H. Different Manifestations of Malignant Melanoma in the Breast:A Report of 12 Cases and a Review of theLiterature.Jpn J Clin Oncol 2005;35 (4): 202-206.

More Related