Total Cell Death and Apoptotic Levels in Human NSC Following Multiple Treatments

DESCRIPTION

This study examines the effects of various treatments (TRAIL, TNF-α, CHX, zVAD-fmk, and Necrostatin) on total cell death and apoptotic levels in human neural stem cells (NSC) at 24-72 hours post-treatment. Additional treatments (IL-1α, TGF-β1, IL-6, PGE2) were applied before irradiation (0-5 Gy) to assess their roles in influencing cell death. Results are expressed as means ± S.D., with statistical significance determined using Student’s t-test (p < 0.05). This research helps understand the therapeutic potential of these agents in NSC.

Download

1 / 1

Feb 16, 2026

Télécharger la présentation

Total Cell Death and Apoptotic Levels in Human NSC Following Multiple Treatments

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

A C * * * * * * * * * B Suppl. Fig. 1. Total cell death and apoptotic levels in human NSC 24-72 h after indicated treatments: (A) TRAIL (50 ng/ml), TNFa (50 ng/ml), CHX (1 mg/ml) zVAD-fmk (40 mM) and Necrostatin (40 mM); (B) IL1a (10 ng/ml), TGFb1 (5 ng/ml), TNFa (50 ng/ml), IL6 (50 ng/ml), PGE2 (10 ng/ml); (C)IL1a (10 ng/ml), PGE2 (10 ng/ml) and TGFb1 (5ng/ml) were added 30 min before irradiation (0-5 Gy). Errorbars represent means + S.D. (p < 0.05, Student’s t test); stars indicate a significant difference.

More Related