1 / 1

Meta-Analysis ICU Intensive Insulin

This meta-analysis evaluates the effects of intensive insulin therapy on 90-day mortality rates and hypoglycemia incidents in ICU settings. Analyzing data from 26 trials involving 13,567 patients, the results indicate no overall effect on mortality (pooled RR 0.93). However, a significant increase in hypoglycemia risk (RR 6.0) was observed in 14 trials with 12,347 patients. Notably, intensive insulin therapy demonstrated a mortality benefit in surgical ICUs (RR 0.63), while no such benefit was found in medical/mixed ICUs (RR 1.00).

moses-marquez
Télécharger la présentation

Meta-Analysis ICU Intensive Insulin

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Meta-Analysis ICU Intensive Insulin Includes NICE-SUGAR • 90 day mortality—no overall effect (pooled RR 0.93) • 26 trials (n=13,567) • ↑ Risk hypoglycemia (RR 6.0) • 14 trials (n=12,347) • Benefit surgical ICUs (RR 0.63) • 5 trials (n=1,972) • Majority VBG SICU study • No benefit medical/mixed ICUs (RR 1.00) Griesdaleet al., Can Med Assoc J. 2009;180:821

More Related