1 / 15

STAPHYLOCOCCUS

STAPHYLOCOCCUS. Eko Budi Koendhori. Taksonomi. Famili : Micrococcaceae Genus : Staphylococcus : Micrococcus : Stomatococcus : Planococcus Ada 35 spesies tp hanya 3 yg penting S. aureus ( coagulase pos) S. epidermidis S. saprophyticus. Dinding Sel Bakteri Gram + dan -.

natalie-romero
Télécharger la présentation

STAPHYLOCOCCUS

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. STAPHYLOCOCCUS Eko Budi Koendhori

  2. Taksonomi • Famili : Micrococcaceae • Genus: Staphylococcus : Micrococcus : Stomatococcus : Planococcus • Ada 35 spesiestphanya 3 ygpenting • S. aureus (coagulase pos) • S. epidermidis • S. saprophyticus

  3. DindingSelBakteri Gram + dan -

  4. Morfologi • Kokus • Diameter ±1 µm • Gram positif • Non motil • Sporaneg • Reaksiempedudanoptokhinneg (resisten) • Pd media cair : tunggal, diplokokus, tetrad, rantai • Aerob/mikroaerob • Tumbuhcepat pd 37⁰ C • 20 ⁰ C pigmenterlihatbaik • Koloni • Bulat, halusmenonjol, berkilau, pigmen pos • S.aureus : kuningemas • S.epidermidis : putih • Hemolisabervariasi • Pd media kaldudananaerobpigmenneg Morfologi Biakan

  5. SifatPertumbuhan • Tumbuh pd hampirsemua media (nutrien, media agar darahdll) • Meragikarbohidrat asamlaktat • Katalasepos • Tahanterhadapkekeringan, panas(50 ⁰ C, 30 mnt, Na Cl 9% • Pekaterhadapheksaklorofen 3 %

  6. Resistensi • -Lactamase(plasmid): PnclnG, ampicillin, ricarcillin, piperacillin • MecAgene (chromosome): Nafcillin, methicillindanoxacillin • Vancomycin-intermediate S. aureus (VISA) suscp MIC ≤ 2μg/ml; intermdt ≤ 4-8 μg/ml ; resist ≥ 16 μg/ml. • Vancomycin-resistant S. aureus (VRSA) : vanA • Plasmid-mediated resist to tetracycline, erythromycin, aminoglycoside • Tolerance

  7. Struktur Antigen • Peptidoglikan: polysaccharide polymer, exoskeleton, rusakolehasamkuatataulisosim, memicuproduksiIL-1 , opsonisasiAB, chemoattractantthdsel PMN, aktivasikomplemen, miripendotoxin • AsamTeikhoat : polimergliserolatauribitolfosfatantigenik. • Prot A : mengikatFcdariIgG • Kapsul: menghambatfagositosis

  8. Enzym& Toxin • Katalase • Koagulase (oksalat & sitratdi plasma) danclumpungfactor (fibrin) • Hyaluronidase, staphylokinase • Exotoxin (α (hemolysin),β (sphingomyelisin),δ(merusakmembranbilogis), (hemolysin)) • Leukocidin(merusaklekosit) • Exfoliative toxin (epidermolytictx) • Toxic shock syndrome toxin-1 • Enterotoxin

  9. Staphylococcus aureus

  10. Identifikasi • 20-50% populasiS.aureus (+) dihidung • β hemolytic pada agar darahdomba • MengfermentasiMannitol • Golden pigmented (aureus)- sering • Koagulase-positif

  11. Penyakit • pneumonia • osteomyelitis • septic arthritis • bacteremia • endocarditis • abscesses/boils • Infeksikulit lain

  12. Keracunanmakanan • Bukaninfeksi • kontaminasimakananolehS.aureus • tumbuh • enterotoxin • Timbuldansembuhnyaterjadidalamhitungan jam

  13. Gejalakeracunanmakanan • muntah • nausea • diare • Nyeriperut

  14. Toxic shock syndrome • Demam • Ruammerah • Deskuamasi • Muntah • Diare • Toxic shock toxin • menyebar • Organism • lokal

More Related