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The Role of Key Genes in Cell Cycle Regulation and Spermatogenesis

This study explores the intricate relationships among key genes involved in the G0-G1 cell cycle transition and spermatogenesis. We focus on the role of genes such as Nras, Itpr3, and Wwtr1 in regulating spermatogonial development, as well as the interactions between various signaling pathways. Key findings reveal how genes like Cdkn1a, Flt1, and Vegfa contribute to cell proliferation and differentiation in male germ cells, offering insights into potential targets for fertility treatments and regenerative medicine.

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The Role of Key Genes in Cell Cycle Regulation and Spermatogenesis

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  1. Csde1 Nras Ccnh Itpr3 Pcnt Prep Ptk2 Stx5a Stx5a Wwtr1 Csde1 Nrp1 Nras Nras Ecd Dok7 Crebzf G0-G1 cell cycle network Spermatogonia Complete Pkd1 Cdkn1a Fhl1 Eps8 Lama2 Itpr3 Pkd2 Tceal1 Egln1 Apbb2 Flt1 Fndc5 Hnrnpk Bai2 Prep Ptk2 Wwtr1 Src Vegfa Bcar1 Sh3bp2 Abl2 Drd2 Kras Crebzf Vegfc Rala Zhx2 Cdk7 Cdk8 Reck Spermatocytes Spermatids Nsg1 Lpxn Nphp3 Sh3glb1 Bcl2 Csdc1 Pbsn Zbtb24 Gpr83 Rin1 Dok7 Vav1 Ptpn22 Cd19 Cd19 E2f4 Lin9 Fkbpl Klk1 Klk6 Cd180 Ccnc G0-G1 Expression Map Ccnh

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