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Pediatric Clinical & Translational Research Center (PCTRC)

Pediatric Clinical & Translational Research Center (PCTRC). University of Pittsburgh Clinical and Translational Science Award. CTSA Pediatric Steering Committee Bethesda, MD March 22, 2007. Integration of Pediatric Research into CTSA.

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Pediatric Clinical & Translational Research Center (PCTRC)

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  1. Pediatric Clinical & Translational Research Center (PCTRC) University of Pittsburgh Clinical and Translational Science Award CTSA Pediatric Steering Committee Bethesda, MD March 22, 2007

  2. Integration of Pediatric Research into CTSA • Since 1962 the Children’s Hospital of Pittsburgh GCRC had a historically successful clinical and translational research program before the CTSA. • CTSA provides a range of participant recruitment and clinical interaction resources (PCIR) that support translational patient-oriented research in pediatrics. • CTSA provides additional resources through collaboration with the CTSI Center for Clinical and Translational Informatics (CCTI) (data management, statistical support etc.) and pilot funding. • CTSA provides extensive educational opportunities that support the research activities of pediatric junior faculty and trainees enrolled in CTSI training programs. • CTSA provides institutional support for large-scale community-based pediatric research outside the PCTRC. • The CTSA will facilitate the development of interdisciplinary research.

  3. Key Challenges for Pediatric Research • Institutional Review Boards (IRB): IRB restrictions hinder meritorious pediatric research Need for uniformity and standardization across IRBs • Shrinking pool of pediatric physician-investigators • Lack of K funding opportunities for International Medical Graduates. • Dwindling NIH funding despair of investigators Junior investigators: “we don’t want this kind of lifestyle!” Senior investigators: “when can I retire?” • The notion that adults are good models for diseases that affect children and adults is wrong. Research in pediatrics should not be swallowed up by research in adults.

  4. Goals for the Pediatric Steering Committee Meeting • Identify problems within the larger structure of the CTSA to insure that pediatric research is not unfairly compromised in favor of other CTSA activities/programs. • To develop qualitative and quantitative processes for comprehensively evaluating and tracking the success of pediatric research within the CTSA and pediatric investigators’ needs. • Work with NIH to develop a timetable to address and successfully overcome the above stated key challenges for pediatric research.

  5. Pediatric Clinical & Translational Research Center (PCTRC) University of Pittsburgh Clinical and Translational Science Award CTSA Pediatric Steering Committee Bethesda, MD March 22, 2007

  6. Participant and Clinical Interaction Resources Core: Organization CTSI Executive Committee Director, PCIR Core Administrative Director, PCIR Administrative Coordination Committee, PCIR Education Participant and Clinical Interaction Resources Informatics Montefiore University Hospital CTRC Children’s Hospital CTRC Pittsburgh Cancer Institute CTRC Regulatory Community CTRC Magee Women’s CTRC Neuroscience CTRC Technologies

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