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AntiBase 2007: Comprehensive Database of Natural Compounds

Explore 33,557 natural compounds from micro-organisms and higher fungi in the AntiBase 2007 database by Prof. Hartmut Laatsch from University of Göttingen. Features structure and text search, property search, and case studies on compound identification and biological activity comparisons.

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AntiBase 2007: Comprehensive Database of Natural Compounds

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  1. Antibase 2007 is a comprehensive database of 33,557 natural compounds from micro-organisms and higher fungi. Prof. Hartmut Laatsch, University of Göttingen

  2. Content

  3. Search Features • Structure search • Text search • Search for properties

  4. Case study: What are the typical biological sources of Antraquinone derivatives?

  5. Case study: Compare the biological activity of Penicillin derivatives!

  6. Case study: compound identification • Optical rotation value of • -270 degree • Elemental analysis: nitrogen positiv, • no sulfur, no halogen • There is a CNMR spectrum with 17 C • shifts

  7. Case study: compound identification • UV: 523, 510, 493, 257, 234, 212 • FAB: M+ = 825 • A HNMR spectrum has been acquired

  8. Case study: compound identification • HRMS 400,267 • IR 3500 1/cm (+ more peaks)

  9. AntiBase is available in the database • Formats: • ChemFinder (CambridgeSoft) • ISIS/Base (MDL) • SciDex (LCI Publisher)

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