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This report provides a comprehensive overview of urinary tract infections (UTIs) in children, detailing risk factors, common symptoms, and effective treatment options. It highlights the differences between lower and upper UTIs, including cystitis and pyelonephritis. Emphasis is placed on age-related risk factors, diagnostic methods, and the role of common pathogens like E. coli. The report also discusses treatment protocols for cystitis and pyelonephritis, emphasizing the importance of follow-up care and management of potential complications.
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Morning Report September 6, 2011
UTIs • Lower • Bladder • Urethra • Upper • Kidneys • Renal pelvis • Ureters
Risk Factors • Age • Infants • Teenagers • Sex • First 3 postnatal months • Males • First 6 years • Females
Risk Factors • Previous history • Sibling with UTI • Catheterization • Structural Abnormalities • Cause complicated UTIs • Most important risk factor for the development of pyelonephritis?? • VUR
Common Bugs • E.coli • 90% • Enterobacter • Proteus • Klebsiella
Defense • Empty bladder regularly
Signs and Symptoms • Younger children and infants • Fever • Irritability • Poor feeding • Lethargy • Abd pain • Vomiting • Loose stools
Signs and Sypmtoms • Older children/adolescents • Cystitis: consist of dysuria, frequency, urgency, suprapubic pain, and/or hematuria • Pyelonephritis:consist of the above symptoms (symptoms of cystitis may or may not be present) together with fever (>38ºC), chills, flank pain, costovertebral angle tenderness, and nausea/vomiting • May mimic PID
To Bag or Not to Bag? • Bag specimen • Bag can only exclude if normal, although in younger kids, they may still have UTI and have normal UA • Urethral catheterization • Suprapubic aspiration • Clean Catch • Older children
Results • Leukocyte esterase • WBCs • Casts are diagnostic of pyelonephritis • Nitrites • Bacteria • Gram stain
Results • Pyelonephritis • Elevated peripheral WBC count • ESR • CRP • None are sensitive or specific enough to include or exclude
Results • Culture results • Diagnostic confirmation • Suprapubic tap • Any growth • Cath • >50,000 • Midstream Catch • >100,000
Imaging • Not needed to confirm diagnosis of pyelo! • U/S • CT • More sensitive • DMSA • Test of choice • Detects renal scarring • Not routinely used
Treatment • Cystitis • Nitrofurantoin • *Avoid if suspected early pyleonephritis due to poor plasma concentration • TMP-SMX • Do not use if local resistance is over 10-20% • Fluoroquinolones
Treatment • Pyleonephritis
Follow up • No f/u culture needed • < 5 years old • Antibiotics until work up complete • Renal U/S • VCUG • Older children may warrant eval if febrile UTI or pyelonephritis occurs
Complications • Bacteremia • Obstruction • Abscess • Recurrence • Renal Scarring • HTN
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