Methylation Patterns of Key Genes in Cancer: RASSF1, SFRP1, and CHRM3 Analysis

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This study investigates the methylation status of critical genes, including RASSF1, SFRP1, PRRT1, CHST11, and CHRM3, to understand their role in cancer. Our analysis reveals significant methylation frequencies, identifying a 70% methylation rate for RASSF1, 81% for SFRP1, and 66% for both CHST11 and CHRM3. By utilizing array-based SBS techniques, our findings suggest that aberrant methylation of these genes may contribute to tumorigenesis and serve as potential biomarkers for early cancer detection.

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May 08, 2026

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Methylation Patterns of Key Genes in Cancer: RASSF1, SFRP1, and CHRM3 Analysis

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A B C D HOXD2 RGMA % Methylation % Methylation E RASSF1 F SFRP1 % Methylation % Methylation G PRRT1 % Methylation H I CHRM3 CHRM3 Array SBS Array SBS 70% 37% CHST11 CHST11 J K 44% 81% ZBTB22 ZBTB22 L M 66% 66%