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Experimental DCBT in SCID Mice: Advantage for NiCord™

Experimental DCBT in SCID Mice: Advantage for NiCord™. 20. 18. 16. 14. 12. 10. 8. 6. 4. 2. 0. Experimental cohorts (n = 10/ cohort). Non cultured CBU (NC): 2 x 10 6. Single. NiCord 2x10 6. CBT. NC CBU-1 (2x10 6 ) + NC CBU-2 (2x10 6 ). Double. CBT.

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Experimental DCBT in SCID Mice: Advantage for NiCord™

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  1. Experimental DCBT in SCID Mice: Advantage for NiCord™ 20 18 16 14 12 10 8 6 4 2 0 Experimental cohorts (n = 10/ cohort) Non cultured CBU (NC): 2 x 106 Single NiCord 2x106 CBT NC CBU-1 (2x106) + NC CBU-2 (2x106) Double CBT NiCord (2x106) + NC (2x106) Short-term engraftment (two weeks post transplant) Chimerismanalysis Double CBT Single CBT * The engrafting unit is CBU-1 CBU-1 Cultured CBU-1 Cultured + CBU-2 Non - cultured CBU-2 Cultured CBU-2 Cultured + CBU-1 Non - cultured ** The engrafting unit is CBU-1, the NAM-cultured unit CD45+ cells (%) ** *** The engrafting unit is CBU-2, the NAM-cultured unit *** CBU-1 Non-cultured + CBU-2 Non-cultured CBU-1 Non-cultured CBU-2 Non-cultured *

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