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Neurocysticercosis

Neurocysticercosis. Jenna Sawafta Infectious Diseases in the Developing World Fall 2012. Neuro -Brain Cysticercosis is an infection due to ingestion of Taenia Solium. http:// drugline.org /medic/term/ taenia /. The most common parasitic disease of the nervous system.

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Neurocysticercosis

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  1. Neurocysticercosis Jenna Sawafta Infectious Diseases in the Developing World Fall 2012

  2. Neuro-Brain Cysticercosis is an infection due to ingestion of TaeniaSolium http://drugline.org/medic/term/taenia/

  3. The most common parasitic disease of the nervous system It is also the main cause of epilepsy in developing countries http://www.cedars-sinai.edu/Patients/Programs-and-Services/Epilepsy-Program/Diagnosing-Epilepsy/

  4. 60-80% of people with the disease become epileptic http://jessicaksmith.blogspot.com/2010/07/45000-sudden-unexplained-deaths-in.html

  5. What does a brain with neurocysticercosis look like? Normal Brain Neurocysticerosis http://emedicine.medscape.com/article/1168656-overview

  6. A closer look… Brain Lesions Brain Lesions http://medicalschool.tumblr.com/post/12376854128/neurocysticercosis-is-an-infection-in-the-brain-of

  7. How is the disease transmitted?

  8. NCC is spread by the fecal oral route http://www.absoluteastronomy.com/topics/Blastocystis

  9. Transmission occurs when pathogens of one host are introduced to the oral cavity of another Egg Intermediate Host Definitive Host http://www.path.cam.ac.uk/~schisto/general_parasitology/parasitology_cestodes_examples.html

  10. Larval form of parasite found in intermediate host (Pig) • Infection of definitive host via: • Uncooked meat • Contaminated meat • Adult form of the parasite manifests in human • Tapeworms lay new eggs in muscle tissue • Development of the tapeworm in the brain http://www.learningradiology.com/archives2010/COW%20397-Cysticercosis/ncccorrect.htm

  11. Most commonly transmitted through food contamination http://img4-2.realsimple.timeinc.net/images/ingredients/ham_300.jpg http://www.whatacrappyjob.com/wp-content/uploads/2009/12/logo-biohazard-252x300.gif

  12. Who does this affect?

  13. 2.5 million people world-wide are living with TaeniaSolium http://radiographics.rsna.org/content/30/6/1705/F2.expansion.html

  14. The most heavily affected countries are in Latin America http://radiographics.rsna.org/content/30/6/1705/F2.expansion.html

  15. Non-endemic countries’ cases are rising because of travel to endemic regions and immigration. http://oldweb.madison.k12.wi.us/tnl/detectives/People_and_Places/Regions/South_America/ http://www.worldtravelforumonline.com/forumindex/images/southamerica1.jpg

  16. How do we treat it?

  17. The main antiparasitic drugs PraziquantalAlbendazole http://www.chemicalland21.com/lifescience/phar/ALBENDAZOLE.htm https://www.healthtap.com/#topics/get-rid-of-threadworms

  18. Clinical trials shows that Albendazole kills 60-85% of brain cysterci in 4 weeks http://www.biomedsearch.com/nih/Albendazole-versus-Praziquantel-in-Treatment/18335068.html

  19. What are we doing about it?

  20. Improving sanitation • Modernizing swine husbandry • Developing detection technology for tapeworms http://www.pigprogress.net/Home/General/2010/12/Balanced-trace-element-feed-improves-sow-performance-PP006960W/

  21. Works Consulted • DeGiorgio, Christopher. "Neurocysticercosis." National Center for Biotechnology. US Library of Medicine, 4 2004. Web. 5 Nov 2012. <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176337/>. • "Examples of Common Cestodes." SRG General Pathology. University of Cambridge, n.d. Web. 06 Nov 2012. <http://www.path.cam.ac.uk/~schisto/general_parasitology/parasitology_cestodes_examples.html>. • "Neurocysticercosis: Radiologic-Pathologic Correlation ." RadioGraphics. Radiological Society of North America, n.d. Web. 10 Nov 2012. <http://radiographics.rsna.org/content/30/6/1705/F2.expansion.html>. • Zafaar, Mohammed. "Neurocysticercosis." MedScape. WebMed LLC, 07 2011. Web. 10 Nov 2012. <http://emedicine.medscape.com/article/1168656-overview • Zimmer, Carl. "Hidden Epidemic: Tapeworms Living Inside Peoples Brains." Discover Magazine. Kalmbach Publishing, 15 2012. Web. 08 Nov 2012. <http://discovermagazine.com/2012/jun/03-hidden-epidemic-tapeworms-in-the-brain>.

  22. Thank you!

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