1 / 1

State of the art and is it used at Pfizer (Sandwich, UK)

State of the art and is it used at Pfizer (Sandwich, UK). Multi-objective “stuff” HTS/random screening HT docking Pharmacophore generation Fragment based approaches Machine learning / data mining Focussed libraries Pipeline Pilot Other workflow tools (knime)

osborn
Télécharger la présentation

State of the art and is it used at Pfizer (Sandwich, UK)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. State of the art and is it used at Pfizer (Sandwich, UK) • Multi-objective “stuff” • HTS/random screening • HT docking • Pharmacophore generation • Fragment based approaches • Machine learning / data mining • Focussed libraries • Pipeline Pilot • Other workflow tools (knime) • QSPR: property prediction • Chemogenomics / chemical biology • Bioisosters ± (we should do more) ++ (standard practise) - (has never worked for us, too slow) - (Other methods work better) + (Hot area but we are still learning) ++ (Large part of my job) + (Often done but design could be better) +++ (Changed our work dramatically) - (It is not free, cost of implementation) + (Not by classic linear QSAR) ++ (Hot area but very new to us) + (part of datamining effort)

More Related