Role of miR-34/449 in Airway Mucin Cell Docking Mechanisms in Mice

Dec 10, 2025

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This study investigates the effects of miR-34/449 deficiency on basal body docking in airway multiciliated cells (MCCs) in mice. The authors, R. Song et al., demonstrate that the lack of these microRNAs disrupts the normal docking process, leading to impaired ciliary function. The findings contribute to our understanding of the molecular mechanisms underlying MCC behavior and have implications for respiratory diseases where ciliary function is compromised. Published in *Nature*, this research highlights the significance of miR-34/449 in maintaining airway health.

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Role of miR-34/449 in Airway Mucin Cell Docking Mechanisms in Mice

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