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Excellent Taste-Barrier with Rapid Dissolution Profile

Excellent Taste-Barrier with Rapid Dissolution Profile. Actimask ® Acetaminophen 92M Taste-Masked. Product Attributes. Excellent taste-barrier with rapid dissolution profile At oral pH, less than 15% released in first minute; no bitter taste

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Excellent Taste-Barrier with Rapid Dissolution Profile

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  1. Excellent Taste-Barrier with Rapid Dissolution Profile Actimask® Acetaminophen 92M Taste-Masked Version 3.0

  2. Product Attributes • Excellent taste-barrier with rapid dissolution profile • At oral pH, less than 15% released in first minute; no bitter taste • Exceeds compendial target: 100% release at 30 minutes • At gastric pH, matches uncoated API release profile • Hydrophilic coating provides superior organoleptic properties • Proprietary aqueous system, no residual solvent • Uniform, smooth hydrogel coating, provides excellent mouthfeel • Uniform particle size: average less than 400 microns (µ) • High assay (92%) reduces tablet weight Version 3.0

  3. ActimaskAcetaminophen 92M Excellent taste-barrier with rapid dissolution profileAt oral pH, low active release in the 1st minute leads to excellent taste-barrier Version 3.0

  4. ActimaskAcetaminophen 92M Excellent taste-barrier with rapid dissolution profileExceeds USP/EP compendial target of 80% in 30 minutes Version 3.0

  5. Actimask Acetaminophen 92M Excellent taste-barrier with rapid dissolution profileIn gastric pH, 92M closely matches uncoated Acetaminophen Version 3.0

  6. Uniform Particle Size average < 400 microns Uniform Smooth Hydrogel Coating d(0.5): 395.543µ Version 3.0

  7. ActimaskAcetaminophen 92MOther Items • Product: Gelatin-coated Acetaminophen • Assay: 92% (+/- 3%) • Pack size: 50 kg drums, with double poly liner and desiccant • Shelf-life: 6 months initially, to be extended based on on-going stability • All ingredients meet USP/NF or EP • FCC compendia ingredient where USP/NF or EP is not available Version 3.0

  8. Actimask Acetaminophen 92M Powder StabilityT6 to be added as completed Version 3.0

  9. Actimask Acetaminophen 92M 250 mg ODT Tablet StabilityT1, T3, T6 to be added as completed Version 3.0

  10. Summary • Excellent taste-barrier with rapid dissolution profile • Hydrophilic coating provides superior organoleptic properties • High assay (92%) reduces tablet weight Get Better Without the Bitter! Version 3.0

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