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بسم الله الرحمن الرحيم

بسم الله الرحمن الرحيم. Leukocytes. Leukopenia Leukocytosis. Leukopenia (Agranulocytosis). Myeloid stem cell suppression Ineffective granulopoisis Heriditary disorders, kostmann syn. Immune destruction Spleenic sequestration Peripheral destruction. Leukocytosis. Normal Lymph node.

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بسم الله الرحمن الرحيم

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  1. بسم الله الرحمن الرحيم

  2. Leukocytes • Leukopenia • Leukocytosis

  3. Leukopenia(Agranulocytosis) • Myeloid stem cell suppression • Ineffective granulopoisis • Heriditary disorders, kostmann syn. • Immune destruction • Spleenic sequestration • Peripheral destruction

  4. Leukocytosis

  5. Normal Lymph node

  6. Lymphadenitis • Acute nonspecific lym. • Chronic non specific lym. • Follicular hyperplasia • Sinus histiocytosis • Paracortical hyperplasis

  7. Neoplastic proliferation of leukocytes • Lymphomas • Leukemias • Plasmacell dyskerasia • Langerhans cell histiocytosis

  8. Lymphoproliferative disorders • Lymphomas • Leukemias • Plasma cell dyscrasia

  9. Myeloid Neoplasms • Acute Leukemias • Chronic Leukemias • Myelodysplastic disorders • Myeloproliferative disorders

  10. Lymphomas • Hodgkins lymphoma (HD) • Non Hodgkins lymphoma (NHL)

  11. Hodgkin's Lymphoma

  12. Non Hodgkin's lymphoma

  13. LeukemiaClassification • Acute Aml , ALL • Chronic CML , CLL

  14. Myeloblast Lymphoblast • Chromatin Fine Clamp • Nucleoli 3 – 5 1- 2 • Granules Variable Non • PA - + • Tdt %5 % 95 • Sudan Black + - • Mpo + -

  15. A.M.L

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