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The Origin and Impact of the Ebola Virus in Zaire

The Ebola virus emerged on August 26, 1976, in Yambuku, Zaire, after a school teacher fell ill following a hike. Initially treated for malaria, his symptoms rapidly progressed to severe vomiting, diarrhea, and bleeding, leading to his death 14 days later. This event triggered an epidemic, claiming the lives of 280 out of 313 infected individuals, a mortality rate of 88%. Research into the virus's natural host included trapping and testing over 1,000 animals, revealing that certain bat species harbored viral nucleotides closely related to those infecting humans, highlighting the interconnectedness of wildlife and human health.

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The Origin and Impact of the Ebola Virus in Zaire

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  1. Story 7.10

  2. The story of Ebola virus

  3. Zaire = Democratic republic of congo

  4. The name Ebola August 26, 1976 in Yambuku, a town in the north of Zaïre. A 44-year-old school teacher returned from a small hike. His went to the doctor and because of his high fever they gave him a quinine shot which is good against malaria. A week later, he had uncontrolled vomiting, bloody diarrhea, trouble breathing and then bleeding from his nose, mouth, and anus. He died ~14 days after the onset of symptoms. He started an epidemic that killed 280 of the 313 infected persons (88%).

  5. Ebola The virus kills gorillas and chimpanzees and other monkeys. Because it kills apes in such high percentage – they are not likely to be its natural host.

  6. Towards detecting the natural host of the virus

  7. Three trapping expeditions in areas close to infected gorilla and chimpanzee carcasses in Gabon and in Congo. 1,030 animals were tested including 679 bats, 222 birds and 129 small terrestrial vertebrates (PCR). Viral nucleotides were discovered in 3 species of bats.

  8. MP and Bayesian analysis support the viruses are closely related to those which have previously infected humans = animal trapped = human infection

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