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What is Pemetrexed? • Pemetrexed is used to treat non-squamous non-small cell lung cancer, or malignant pleural mesothelioma (a form of lung cancer associated with exposure to asbestos). • Pemetrexedis sometimes used in combination with other cancer medicines. • Warnings • Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. • Before taking this medicine • You should not be treated with pemetrexed if you are allergic to it. • Tell your doctor if you have ever had: • kidney disease; or • radiation treatment. Source: https://www.drugs.com/mtm/pemetrexed.html
How is Pemetrexedgiven? • Pemetrexed is given as an infusion into a vein. A healthcare provider will give you this injection. • Pemetrexed is usually given every 3 weeks. Your doctor will determine how many treatment cycles you should receive. • To prevent certain side effects of pemetrexed, you will need to take folic acid supplements and receive vitamin B12 injections (starting 7 days before your first dose of pemetrexed). Take only the amount of folic acid that your doctor has prescribed. • Your doctor may also prescribe steroid medication to reduce certain side effects of pemetrexed. Follow your doctor's dosing instructions very carefully. • Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking pemetrexed. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure. Source: https://www.drugs.com/mtm/pemetrexed.html
What happens if I miss a dose? • Call your doctor for instructions if you miss an appointment for your pemetrexed injection. • What happens if I overdose? • Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. • What should I avoid while receiving pemetrexed? • If you have kidney disease, avoid taking ibuprofen (Advil, Motrin) for 2 days before or 2 days after you are treated with pemetrexed. • Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. • Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. Source: https://www.drugs.com/mtm/pemetrexed.html
Pemetrexed • Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). • Call your doctor at once if you have: • little or no urination; • new or worsening cough, fever, trouble breathing; • swelling, redness, or blistering of skin that was treated with radiation in the past; or • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath. Source: https://www.drugs.com/mtm/pemetrexed.html
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