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Diagnosis: Desmoplastic Melanocytic Nevus

A 26-year-old male presents with a raised nodule on his left arm with a collarette. Neoplastic proliferation is noted in the expanded papillary dermis. S-100 strongly positive, CD-68 negative in neoplastic cells, CD-34 positive in blood vessels.

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Diagnosis: Desmoplastic Melanocytic Nevus

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  1. What is your diagnosis? Deba P Sarma, MD Omaha

  2. M 26, left arm -Raised nodule with collarette. -Neoplastic proliferation is in the expanded papillary dermis

  3. S-100 : Strongly positive

  4. CD 68: Neoplastic cells are negative

  5. CD 34: Blood vessels are positive

  6. Diagnosis: Desmoplasticmelanocytic nevus • Other names: • Desmoplastic nevus(Desmoplastic Spitz nevus,Desmoplasticepitheliod cell nevus,Desmoplasticmelanocytic nevus)

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