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Impact of PCNA on Ligase III Function in DNA Repair Mechanisms

This study examines the role of Proliferating Cell Nuclear Antigen (PCNA) in the regulation of Ligase III activity during DNA repair processes. By analyzing the interaction dynamics between PCNA and Ligase III, we explore their combined influence on DNA damage responses. The results highlight significant findings regarding the mechanistic pathways of DNA repair and the collaborative functions of these proteins. Understanding this relationship is crucial for advancing therapeutic strategies targeting DNA repair deficiencies associated with various diseases.

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Impact of PCNA on Ligase III Function in DNA Repair Mechanisms

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  1. A AS3WT2 46Br.1G1 LigIII PCNA merge LigIII PCNA merge B ESM Fig 2

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