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The mechanism of blood clotting

The mechanism of blood clotting. The necessity of blood clotting. Damaged blood vessels, tissues or blood platelets. Calcium ions (Ca 2t ). Vitamin K. Thrombokinase ( thromboplastin ). Prothrombin (inactive). thrombin (active). Fibrin (insoluble). Fibrinogen (soluble).

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The mechanism of blood clotting

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  1. The mechanism of blood clotting Tr.Rez@SB2014

  2. Tr.Rez@SB2014 The necessity of blood clotting

  3. Tr.Rez@SB2014

  4. Tr.Rez@SB2014 Damaged blood vessels, tissues or blood platelets Calcium ions (Ca2t) Vitamin K Thrombokinase (thromboplastin) Prothrombin (inactive) thrombin (active) Fibrin (insoluble) Fibrinogen (soluble) Fibrin mesh traps red blood cells which dry up to form a blood clot

  5. Tr.Rez@SB2014 Impaired Blood Clotting Mechanism • Impaired blood clotting mechanism: • Making the blood clotting impossible or • Causing blood to clot blocking the flow of blood within the blood vessels

  6. Tr.Rez@SB2014 Deficient in calcium & vitamin K • Calcium & vitamin K must be present in blood for the formation of blood clots • If body does not have enough Ca & Vit K; take longer time to clot • If totally missing, person who suffers a cut could bleed to death

  7. Tr.Rez@SB2014 Haemophilia • have an impaired blood-clotting mechanism • blood is unable to form a clot • due to the deficiency in the blood proteins taking part in coagulation • haemophiliacs • may bleed to death or die of internal injury

  8. Tr.Rez@SB2014 Thrombosis • formation of a clot / thrombus inside a blood vessel • blocking blood flow • stops the tissues from receiving the normal blood flow & oxygen • If not treated quickly, can cause damage / death of tissues in that area • Clot in coronary artery : heart attack • Clot in brain : stroke

  9. Deep Vein Thrombosis Tr.Rez@SB2014

  10. Tr.Rez@SB2014 Coronary thrombosis

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