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Nordic Reference Interval Project (NOBIDA) - Biobank and Database Overview

The Nordic Reference Interval Project (NOBIDA) aims to establish reference intervals and collect data for various biomarkers through a collaborative biobank and database across the Nordic countries. The project, meeting in Malmö on April 27, 2004, involves contributions from medical laboratories and institutions from Denmark, Iceland, Finland, Norway, and Sweden. Biobank samples including serum, plasma, and buffy coat are collected for analysis, while extensive data is gathered on measurement values, instruments, and patient questionnaires to improve healthcare diagnostics.

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Nordic Reference Interval Project (NOBIDA) - Biobank and Database Overview

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  1. NORIP, Malmø 27/4-2004 NOBIDANordic Reference Interval ProjectBiobank and Database Common Nordic Reference Intervals NFKK meeting 27/4-2004 Pål Rustad Fürst Medical Laboratory, Oslo http://www.furst.no/norip/nobida

  2. NORIP, Malmø 27/4-2004 NOBIDANordic Reference Interval Project Bio- and Data Bank • Established by NFKK • Bio-bank location DEKS Danish Institute for External Quality Assurance for Laboratories in Health CareHerlev University hospital, Copenhagen • Databank location Fürst Medical Laboratory, Oslo • NOBIDA commitee Ulrik Gerdes (Denmark), Jón Jóhannes Jónsson (Iceland), Veli Kairisto (Finland), Arne Mårtensson (Sweden), Pål Rustad (Norway)

  3. NORIP, Malmø 27/4-2004 Bio-bank • Samples from each reference individual • 7x1 mL serum • 2x1 mL Li-heparin plasma • 1 mL buffy coat • Reference materials • NFKK Reference serum X: 3000x5 mL • HIGH, LOW, P: ~300x2,5 mL (~1500 mL in bulk)

  4. NORIP, Malmø 27/4-2004 NOBIDANordic Reference Interval Project Bio- and Data Bank

  5. NORIP, Malmø 27/4-2004 Data baseType of data • Reference individuals • Data from questionnaire • Measurement system • Instrument manufacturer and name • Method group and name • Measurement values • Controls and reference samples

  6. NORIP, Malmø 27/4-2004 DatabaseMeasurement values

  7. NORIP, Malmø 27/4-2004 Applicationfor sampels and data Application form: http://furst.no/norip/nobida Applications at the moment 1. Comparisons with the experiences in the local Southern Osthrobothnia Project Requested: Data on all components 2. Establishment of reference intervals for CEA, CA125, MUC1, Thyroglobulin (and autobodies), NSE, PSA (total and free), SCCA, ProGRP, AFP, CA19.9, HCG. Requested: 250 samples for each gender. 3. Evaluation of formulas for calculation of creatinine clearance based on gender, age, weight and measured S-creatinine. Requested: All data on creatinine

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